MULTISPECIES: sensor domain-containing diguanylate cyclase

LOCUS       WP_003101151             375 aa            linear   BCT 24-DEC-2024
            [Pseudomonas].
ACCESSION   WP_003101151
VERSION     WP_003101151.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 375)
  AUTHORS   Simm,R., Fetherston,J.D., Kader,A., Romling,U. and Perry,R.D.
  TITLE     Phenotypic convergence mediated by GGDEF-domain-containing proteins
  JOURNAL   J Bacteriol 187 (19), 6816-6823 (2005)
   PUBMED   16166544
  REMARK    Erratum:[J Bacteriol. 2006 Mar;188(5):2024]
REFERENCE   2  (residues 1 to 375)
  AUTHORS   Aravind,L. and Ponting,C.P.
  TITLE     The GAF domain: an evolutionary link between diverse
            phototransducing proteins
  JOURNAL   Trends Biochem Sci 22 (12), 458-459 (1997)
   PUBMED   9433123
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13413304
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..375
                     /product="sensor domain-containing diguanylate cyclase"
                     /EC_number="2.7.7.65"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /calculated_mol_wt=42216
     Region          10..>366
                     /region_name="COG5001"
                     /note="Cyclic di-GMP metabolism protein, combines GGDEF
                     and EAL domains with a 6TM membrane domain [Signal
                     transduction mechanisms]"
                     /db_xref="CDD:444025"
     Region          213..366
                     /region_name="GGDEF"
                     /note="Diguanylate-cyclase (DGC) or GGDEF domain; cd01949"
                     /db_xref="CDD:143635"
     Site            order(248,291)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:143635"
     Site            order(253,256..257,261,265,287,289..292)
                     /site_type="active"
                     /db_xref="CDD:143635"
     Site            order(283,311)
                     /site_type="active"
                     /note="I-site [active]"
                     /db_xref="CDD:143635"
ORIGIN      
        1 mrtdkpplkq ralqklllrr fgmaagtyll glvllwlall sgfyraaptt aaasttlvva
       61 cqlaflwlfa sgrnlryadp sltepqvlva iawltyflyh vdslrgtfmv fyvlallfgv
      121 fqlpprvfar caalafiafs giylvealqq rlelpgraal qvlvmfivmv wlslfasyiq
      181 amrqrmrqrr yalqahqdtl rgmmrqledl vatdeltglf nrrhfmrmas raledllpnr
      241 qhglalidld hfkrindrhg haagdrvlqt faavarsclr dgdvlarygg eefvlllpha
      301 daeqlescce rlrlafqqae pvgvtvdtls lsvgmtllya dddldealqr adqalyrakr
      361 ggrnrcdatw evtsa