MULTISPECIES: cation:proton antiporter [Pseudomonas].

LOCUS       WP_003100653             611 aa            linear   BCT 23-DEC-2024
ACCESSION   WP_003100653
VERSION     WP_003100653.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 611)
  AUTHORS   Malo,M.E. and Fliegel,L.
  TITLE     Physiological role and regulation of the Na+/H+ exchanger
  JOURNAL   Can J Physiol Pharmacol 84 (11), 1081-1095 (2006)
   PUBMED   17218973
REFERENCE   2  (residues 1 to 611)
  AUTHORS   Alexander,R.T. and Grinstein,S.
  TITLE     Na+/H+ exchangers and the regulation of volume
  JOURNAL   Acta Physiol (Oxf) 187 (1-2), 159-167 (2006)
   PUBMED   16734752
REFERENCE   3  (residues 1 to 611)
  AUTHORS   Hayashi,H., Szaszi,K. and Grinstein,S.
  TITLE     Multiple modes of regulation of Na+/H+ exchangers
  JOURNAL   Ann N Y Acad Sci 976, 248-258 (2002)
   PUBMED   12502567
REFERENCE   4  (residues 1 to 611)
  AUTHORS   Burckhardt,G., Di Sole,F. and Helmle-Kolb,C.
  TITLE     The Na+/H+ exchanger gene family
  JOURNAL   J Nephrol 15 Suppl 5, S3-S21 (2002)
   PUBMED   12027219
REFERENCE   5  (residues 1 to 611)
  AUTHORS   Dibrov,P. and Fliegel,L.
  TITLE     Comparative molecular analysis of Na+/H+ exchangers: a unified
            model for Na+/H+ antiport?
  JOURNAL   FEBS Lett 424 (1-2), 1-5 (1998)
   PUBMED   9537504
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10000258
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..611
                     /product="cation:proton antiporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015078 - proton transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=65483
     Region          6..514
                     /region_name="NhaP"
                     /note="NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion
                     transport and metabolism]; COG0025"
                     /db_xref="CDD:439796"
ORIGIN      
        1 mdqnaillal ggigaaalls qwlawrlrlp ailflllsgi vagpllgwld pdemfgpllf
       61 plvslavali lfegsltlhf sewkeigtvv hrmvtigals twgvialaah ylldfswema
      121 llfgtltlvt gptvivpmlr vvrpkaavan ilrwegivid pigallavvv ysfiissgeg
      181 dgwlhslqtf ggvilcgslf gilggwalgi vlrrhwlpdy lhnlatlaav lgvfiasnrv
      241 mhesgllavt lmgmglanmk gvdvrqilhf kenlsvllis glfillaarl dinallglgp
      301 aallvllliq fvarplnval stwgsplswr erallswiap rgivaaavsa ifairlsaeg
      361 haqaallvpl tflviigtvv lqsatarpla rllkvaepsp sgylivganp vgraigkalk
      421 slgsrvlltd ssweniraar mdnlptyfgn ptsqhaeahl dlvgighllg vspagelntl
      481 aamrfrhefg hrqlfglpts qeakrtdkhr ssdehrgrpl gqrpltyaqf asllsrgaei
      541 rttlltdtfg wndyqalhge saillfardp ngrmhvatpq stlapgtgwt llslidaeps
      601 vsksqateia d