MULTISPECIES: leucine--tRNA ligase [Pseudomonas].

LOCUS       WP_003100324             873 aa            linear   BCT 23-MAY-2024
ACCESSION   WP_003100324
VERSION     WP_003100324.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 873)
  AUTHORS   Liu,Y., Liao,J., Zhu,B., Wang,E.D. and Ding,J.
  TITLE     Crystal structures of the editing domain of Escherichia coli
            leucyl-tRNA synthetase and its complexes with Met and Ile reveal a
            lock-and-key mechanism for amino acid discrimination
  JOURNAL   Biochem J 394 (Pt 2), 399-407 (2006)
   PUBMED   16277600
REFERENCE   2  (residues 1 to 873)
  AUTHORS   Fukunaga,R. and Yokoyama,S.
  TITLE     Aminoacylation complex structures of leucyl-tRNA synthetase and
            tRNALeu reveal two modes of discriminator-base recognition
  JOURNAL   Nat Struct Mol Biol 12 (10), 915-922 (2005)
   PUBMED   16155584
REFERENCE   3  (residues 1 to 873)
  AUTHORS   Zhao,M.W., Zhu,B., Hao,R., Xu,M.G., Eriani,G. and Wang,E.D.
  TITLE     Leucyl-tRNA synthetase from the ancestral bacterium Aquifex
            aeolicus contains relics of synthetase evolution
  JOURNAL   EMBO J 24 (7), 1430-1439 (2005)
   PUBMED   15775966
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00396.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..873
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..873
                     /gene="leuS"
     Protein         1..873
                     /product="leucine--tRNA ligase"
                     /EC_number="6.1.1.4"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /calculated_mol_wt=97517
     Region          1..873
                     /region_name="LeuS"
                     /note="Leucyl-tRNA synthetase [Translation, ribosomal
                     structure and biogenesis]; COG0495"
                     /db_xref="CDD:440261"
ORIGIN      
        1 mheqyqplei etqaqnywke hqsflvrelp dkekfyclsm fpypsgklhm ghvrnytigd
       61 visryhrmqg rnvlqpmgwd afgmpaenaa mknnvapaaw tydniaymks qldslglaid
      121 wsrevttckp dyyrweqwlf trlfekgviy rkngtvnwdp vdqtvlaneq vidgrgwrsg
      181 aliekreipm yyfkitayae ellesldnlp gwpeqvktmq rnwigksrgm eigfpydqas
      241 ighagqlkvf ttrpdtlmga tyvavaaehp latqaaqndp qlqafideck rggvaeadia
      301 tqekkgmats lfvehpltgd klpvwvanyv lmnygegavm avpghderdf efankyglpi
      361 rqviakvegd ndfessvwke wygakdesvl tvnsgkydnl gyqaafdaig adleakglgq
      421 artqfrlrdw gisrqrywgc pipiihceac gdvpvpadql pvvlpedvvp dgsgsplakm
      481 pefyecncpk cgqpakretd tmdtfvessw yfaryacpqf eggmldrkaa dywlpvdqyi
      541 ggiehailhl lyarffhklm rdeglvgsde pfknlltqgm vvadtyyrtt anggkdwfnp
      601 adveverdak akvvgarlks dgqpveiggt ekmsksknng vdpqsmidqy gadtcrlfmm
      661 fasppdmsle wsdagvegan rflrrvwrla hahvsaglpg aldvaalsda qkqvrraihl
      721 airqasqdvg qhhkfntaia avmtlmnvle kapnqdaqdr aliqegletv vlllapitph
      781 ichvlwgqlg haeavidarw psvdesalvq dtlqlvvqvn gklrghidva asasredvea
      841 aaranenvlr fteglsirkv ivvpgklvni van