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LOCUS WP_003100297 437 aa linear BCT 01-JAN-2025 protein [Pseudomonas]. ACCESSION WP_003100297 VERSION WP_003100297.1 KEYWORDS RefSeq. SOURCE Pseudomonas ORGANISM Pseudomonas Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae. REFERENCE 1 (residues 1 to 437) AUTHORS Okawa,F., Hama,Y., Zhang,S., Morishita,H., Yamamoto,H., Levine,T.P. and Mizushima,N. TITLE Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1 JOURNAL J Cell Sci 134 (8) (2021) PUBMED 33771928 REFERENCE 2 (residues 1 to 437) AUTHORS Doerrler,W.T., Sikdar,R., Kumar,S. and Boughner,L.A. TITLE New functions for the ancient DedA membrane protein family JOURNAL J Bacteriol 195 (1), 3-11 (2013) PUBMED 23086209 REFERENCE 3 (residues 1 to 437) AUTHORS Littlechild,J., Garcia-Rodriguez,E., Dalby,A. and Isupov,M. TITLE Structural and functional comparisons between vanadium haloperoxidase and acid phosphatase enzymes JOURNAL J Mol Recognit 15 (5), 291-296 (2002) PUBMED 12447906 REFERENCE 4 (residues 1 to 437) AUTHORS Neuwald,A.F. TITLE An unexpected structural relationship between integral membrane phosphatases and soluble haloperoxidases JOURNAL Protein Sci 6 (8), 1764-1767 (1997) PUBMED 9260289 REFERENCE 5 (residues 1 to 437) AUTHORS Hemrika,W., Renirie,R., Dekker,H.L., Barnett,P. and Wever,R. TITLE From phosphatases to vanadium peroxidases: a similar architecture of the active site JOURNAL Proc Natl Acad Sci U S A 94 (6), 2145-2149 (1997) PUBMED 9122162 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 11426593 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..437 /organism="Pseudomonas" /db_xref="taxon:286" Protein 1..437 /product="bifunctional DedA family/phosphatase PAP2 family protein" /EC_number="3.1.3.-" /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_function="GO:0016791 - phosphatase activity [Evidence IEA]" /GO_process="GO:0008610 - lipid biosynthetic process [Evidence IEA]" /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]" /calculated_mol_wt=46913 Region 1..202 /region_name="DedA" /note="Membrane integrity protein DedA, putative transporter, DedA/Tvp38 family [Cell wall/membrane/envelope biogenesis]; COG0586" /db_xref="CDD:440351" Region 229..397 /region_name="PAP2_like_2" /note="PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; cd03392" /db_xref="CDD:239486" Site order(299,306,321..323,365,371,375) /site_type="active" /db_xref="CDD:239486" ORIGIN 1 msldsfnawm aanpewlgla ifliafleca aivgivlpgv vllfgvavia gsgalglget 61 lllayaggvl gdlssywigr rfhqnirrlp glrshpqwit aaevyferyg iasllvgrfi 121 galrpmlpmv agmldmpfgr flgvsliaaa gwavayllpg watgaalrlp lpegfwseag 181 ivaaclavlv gvvvqaslrr krwatavaaa lslvlllamt vawpylqdld qglmtlvqeh 241 rnadlnpvmv vvtrlgdfrt qfiagallgg illltrqwrp aifaigtlvg talanqtlkt 301 lfararpevl aeplssfsfp sghssasfaf fltlgvlasr qqpprwrltw vllavipsls 361 ialsrvylgv hwpsdivaga llattvcaas lwlsqrresl palpqrvwwl llpvcvatla 421 iaagwalpea iaryrpl