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MULTISPECIES: spinster family MFS transporter [Pseudomonas].


LOCUS       WP_003099328             457 aa            linear   BCT 23-DEC-2024
ACCESSION   WP_003099328
VERSION     WP_003099328.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 457)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 457)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023647
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..457
                     /product="spinster family MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006869 - lipid transport [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=48956
     Region          18..421
                     /region_name="MFS_spinster_like"
                     /note="Protein spinster and spinster homologs of the Major
                     Facilitator Superfamily of transporters; cd17328"
                     /db_xref="CDD:340886"
     Site            order(28..29,32..33,36,69,119..120,122..124,127,147,
                     150..151,154,243,246..247,250..252,255,284,288,340..341,
                     345,349,369,372..373,376..377,380)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340886"
ORIGIN      
        1 mhnnnngyps nlaawttvai lmvayvlsfi drqilnllvg pirrdlaisd temsllmgls
       61 falfytlcgi plgrmadnrs rrglilfgvl vwsamtaacg larsywqflt frvgvgvgea
      121 alspaaysli adsfprerra taisvysmgi ylgsglafll gglvikfasa qgdvhlplfg
      181 evrpwqlifl ilgaagvlfc llllairepa rrgvgagvav plgevgaylr anrktvlchn
      241 fgfaclsfag ygsgawvptf fvrthgwdag hvgvvygsiv avfgclgivf ggrladywak
      301 rgrsdanmrv gllaawavip ftlvyplldn anwaaalmap tvfflsmpfg vapaaiqeim
      361 pnsmrgqasa iylfvvtlfg lgvgptaval vtdfvfaddm alryslllvt laavlgavvl
      421 lgiglkpyra slehlkdwsl rregeggedw kasrqpa