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MULTISPECIES: exodeoxyribonuclease III [Pseudomonas].


LOCUS       WP_003098313             259 aa            linear   BCT 02-JUN-2024
ACCESSION   WP_003098313
VERSION     WP_003098313.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 259)
  AUTHORS   Mathieu,A., O'Rourke,E.J. and Radicella,J.P.
  TITLE     Helicobacter pylori genes involved in avoidance of mutations
            induced by 8-oxoguanine
  JOURNAL   J Bacteriol 188 (21), 7464-7469 (2006)
   PUBMED   16936028
REFERENCE   2  (residues 1 to 259)
  AUTHORS   Georg,J., Schomacher,L., Chong,J.P., Majernik,A.I., Raabe,M.,
            Urlaub,H., Muller,S., Ciirdaeva,E., Kramer,W. and Fritz,H.J.
  TITLE     The Methanothermobacter thermautotrophicus ExoIII homologue Mth212
            is a DNA uridine endonuclease
  JOURNAL   Nucleic Acids Res 34 (18), 5325-5336 (2006)
   PUBMED   17012282
REFERENCE   3  (residues 1 to 259)
  AUTHORS   Shida,T., Ogawa,T., Ogasawara,N. and Sekiguchi,J.
  TITLE     Characterization of Bacillus subtilis ExoA protein: a
            multifunctional DNA-repair enzyme similar to the Escherichia coli
            exonuclease III
  JOURNAL   Biosci Biotechnol Biochem 63 (9), 1528-1534 (1999)
   PUBMED   10540738
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00633.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..259
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..259
                     /product="exodeoxyribonuclease III"
                     /EC_number="3.1.11.2"
                     /GO_function="GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /calculated_mol_wt=29714
     Region          1..253
                     /region_name="Nape_like_AP-endo"
                     /note="Neisseria meningitides Nape-like subfamily of the
                     ExoIII family purinic/apyrimidinic (AP) endonucleases;
                     cd10281"
                     /db_xref="CDD:197336"
     Site            order(7,9..14,35,37,42,64..65,93,108,111,113,118,148,150,
                     160,162,164,203,205..207,209,213,215,217,219..220,243,
                     245..246)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:197336"
     Site            order(7,9..14,35,37,42,64..65,93,108,111,113,118,148,150,
                     160,162,164,203,205..207,213,215,217,219,243,246)
                     /site_type="other"
                     /note="putative DNA binding site [nucleotide binding]"
                     /db_xref="CDD:197336"
     Site            order(7,35,108,111,148,150,246)
                     /site_type="other"
                     /note="putative phosphate binding site [ion binding]"
                     /db_xref="CDD:197336"
     Site            order(7,35,108,148,150,220,245..246)
                     /site_type="active"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:197336"
     Site            order(9,35,245)
                     /site_type="metal-binding"
                     /note="metal binding site A [ion binding]"
                     /db_xref="CDD:197336"
     Site            order(108,111,148,150,203,217,219,246)
                     /site_type="other"
                     /note="putative AP binding site [nucleotide binding]"
                     /db_xref="CDD:197336"
     Site            order(148,150,246)
                     /site_type="other"
                     /note="putative metal binding site B [ion binding]"
                     /db_xref="CDD:197336"
ORIGIN      
        1 mriisvnvng iqaaaergll swlqaqnadv iclqdtrasa fdlddpsfql dgyflyacda
       61 elpeqggval ysrlqpkavi sglgfetadr ygrylqadfd kvsiatlllp sgqsgdesln
      121 qkfkfmddft hylskqrrkr reyiycgsly vahqkmdvkn wrecqqmpgf laperawlde
      181 vfgnlgyada lrevsregdq fswwpdseqa emlnlgwrfd yqvltpglrr fvrnaklprq
      241 prfsqhapli vdydwqlsi