MULTISPECIES: thiamine pyrophosphate-dependent enzyme

LOCUS       WP_003098265             572 aa            linear   BCT 26-FEB-2025
            [Pseudomonas].
ACCESSION   WP_003098265
VERSION     WP_003098265.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 572)
  AUTHORS   Arjunan,P., Umland,T., Dyda,F., Swaminathan,S., Furey,W., Sax,M.,
            Farrenkopf,B., Gao,Y., Zhang,D. and Jordan,F.
  TITLE     Crystal structure of the thiamin diphosphate-dependent enzyme
            pyruvate decarboxylase from the yeast Saccharomyces cerevisiae at
            2.3 A resolution
  JOURNAL   J Mol Biol 256 (3), 590-600 (1996)
   PUBMED   8604141
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF014794.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF02775.26
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..572
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..572
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /calculated_mol_wt=62190
     Region          3..572
                     /region_name="PRK09124"
                     /note="ubiquinone-dependent pyruvate dehydrogenase"
                     /db_xref="CDD:181661"
ORIGIN      
        1 msskkvaeiv vetleaagvr hcygivgdtl nhvtdaihrs qiqwvhvrhe eaaafaagae
       61 syisgrltac agscgpgslh fingvyeaqr nrapmvlias qivtpqlgme fpqevdfkav
      121 yascsvfceq vhspeqarrv valacqaaln rrgvavvilp adisqatvkd dlpfsvhfpq
      181 pvlrpsdael qdvarllahg kkigiyagsg cqgahdllva ladrlkapia htsrakdfve
      241 ydnpfnmgmt gmlgiesgfh mmtecdtlll lgadfawaqf ypqkatliqv drdgshlgrr
      301 hpidlgvvgd viptleallp lleareersf ldeclehrer slrtlekeeq agkgelihpq
      361 hlvslldqha sedalftadg gsamvwllrh ihsngkrrtl tslvhgtman ampqalglkk
      421 ayperqvisi sgdgglamll gdlltaiqek lpikvvvlnn aslnfveleq kveglldnyt
      481 dllnpdfarl aevigfhgrk vtrseeleaa vqeflaqpgp alldvhtnpa elvmppkief
      541 gqvadtalya akavlsgrfk dvetllvnnl lk