MULTISPECIES: sensor domain-containing diguanylate cyclase

LOCUS       WP_003098203             401 aa            linear   BCT 23-DEC-2024
            [Pseudomonas].
ACCESSION   WP_003098203
VERSION     WP_003098203.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 401)
  AUTHORS   Simm,R., Fetherston,J.D., Kader,A., Romling,U. and Perry,R.D.
  TITLE     Phenotypic convergence mediated by GGDEF-domain-containing proteins
  JOURNAL   J Bacteriol 187 (19), 6816-6823 (2005)
   PUBMED   16166544
  REMARK    Erratum:[J Bacteriol. 2006 Mar;188(5):2024]
REFERENCE   2  (residues 1 to 401)
  AUTHORS   Aravind,L. and Ponting,C.P.
  TITLE     The GAF domain: an evolutionary link between diverse
            phototransducing proteins
  JOURNAL   Trends Biochem Sci 22 (12), 458-459 (1997)
   PUBMED   9433123
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13413304
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..401
                     /product="sensor domain-containing diguanylate cyclase"
                     /EC_number="2.7.7.65"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /calculated_mol_wt=44641
     Region          1..>392
                     /region_name="COG5001"
                     /note="Cyclic di-GMP metabolism protein, combines GGDEF
                     and EAL domains with a 6TM membrane domain [Signal
                     transduction mechanisms]"
                     /db_xref="CDD:444025"
     Region          233..391
                     /region_name="GGDEF"
                     /note="Diguanylate-cyclase (DGC) or GGDEF domain; cd01949"
                     /db_xref="CDD:143635"
     Site            order(268,312)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:143635"
     Site            order(273,276..277,281,285,308,310..313)
                     /site_type="active"
                     /db_xref="CDD:143635"
     Site            order(304,332)
                     /site_type="active"
                     /note="I-site [active]"
                     /db_xref="CDD:143635"
ORIGIN      
        1 mlardslvqa glpdnpyarq lrngfrwlrf ekelenefre flswnslmqr raaigvafli
       61 walfivadwm mvdirlhpsl feqllgvrlg miglllvvwp aaflpslrkv gdaiapycll
      121 linlavlacd vlfewhgvpr ftqlgatlgi lavffplgla fwacvrlall clalnlavfl
      181 lfggeenlrt nllntlyngl vvlicsfaly lqdyaqreqf lgrrllgmma eqdsltglvn
      241 rryyellaqr aleqgareek gvalilvdvd dfkayndhyg hpagdaalrq lgvvlrqgar
      301 rpldiaarlg geefavllyd seegntlaia erlrqaveal giehlgssag pcltislgva
      361 ystsgmglda lyreadraly eakdagrnav rvafrqhdrl e