MULTISPECIES: MFS transporter [Pseudomonas].

LOCUS       WP_003097074             435 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003097074
VERSION     WP_003097074.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 435)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 435)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 435)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024287
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..435
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=47630
     Region          23..427
                     /region_name="MFS_KgtP"
                     /note="Alpha-ketoglutarate permease of the Major
                     Facilitator Superfamily of transporters; cd17367"
                     /db_xref="CDD:340925"
     Site            order(33..34,37..38,41,79,137..138,140..142,145,165,
                     168..169,172,252,255..256,259..261,264,292,296,349..350,
                     354,358,374,377..378,381..382,385)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340925"
ORIGIN      
        1 mesanaisas aqprttsqri ksifsgsvgn lvewydwyvy aafslyfaka ffpqgdmtaq
       61 llntaaifav gflmrpiggw lmgiyadrkg rkaallasvl lmcfgsliia ltpsyetigv
      121 aapillvvar llqglsvgge ygtsatylse mankeqrgff ssfqyvtlis gqlialavli
      181 vlqqtltveq leswgwrvpf figalcavva mflrrgmeet esfskkkeep kesllrtllr
      241 hpkevltvvg ltmggtlafy tyttymqkyl vntvgmsktd stmisaatlf lfmllqpivg
      301 alsdkigrrp iliafgvlgt vftypilstl hsvdswwgaf flimaalviv sgytsinavv
      361 kaelfpteir algvglpyal tvsifggtae yvalwfksvg lesgfywyvt aciacsllvy
      421 vfmkdtqkhs kittd