MULTISPECIES: glycine-betaine demethylase subunit GbcA

LOCUS       WP_003096766             429 aa            linear   BCT 20-NOV-2023
            [Pseudomonas].
ACCESSION   WP_003096766
VERSION     WP_003096766.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 429)
  AUTHORS   Wargo,M.J.
  TITLE     Choline catabolism to glycine betaine contributes to Pseudomonas
            aeruginosa survival during murine lung infection
  JOURNAL   PLoS ONE 8 (2), e56850 (2013)
   PUBMED   23457628
REFERENCE   2  (residues 1 to 429)
  AUTHORS   Wargo,M.J., Szwergold,B.S. and Hogan,D.A.
  TITLE     Identification of two gene clusters and a transcriptional regulator
            required for Pseudomonas aeruginosa glycine betaine catabolism
  JOURNAL   J. Bacteriol. 190 (8), 2690-2699 (2008)
   PUBMED   17951379
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR005965
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..429
                     /gene="gbcA"
     Protein         1..429
                     /product="glycine-betaine demethylase subunit GbcA"
                     /calculated_mol_wt=48535
     Region          31..411
                     /region_name="HcaE"
                     /note="Phenylpropionate dioxygenase or related
                     ring-hydroxylating dioxygenase, large terminal subunit
                     [Inorganic ion transport and metabolism, General function
                     prediction only]; COG4638"
                     /db_xref="CDD:443676"
     Region          185..412
                     /region_name="RHO_alpha_C_GbcA-like"
                     /note="C-terminal catalytic domain of GbcA (glycine
                     betaine catabolism A) from Pseudomonas aeruginosa PAO1 and
                     related aromatic ring hydroxylating dioxygenases; cd08884"
                     /db_xref="CDD:176893"
     Site            order(202..203,207,210..211,214,216..217,221,336..337,
                     374..376,378..382,393..395,397,401,404,408)
                     /site_type="other"
                     /note="putative alpha subunit interface [polypeptide
                     binding]"
                     /db_xref="CDD:176893"
     Site            order(211..212,214..215,217..218,222,306..307,309,317,319,
                     326,328,358,361..362,368..369,372)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:176893"
     Site            order(211..212,214..215,217..218,222,306..307,309,317,319,
                     326,328,358,361..362,368..369)
                     /site_type="other"
                     /note="putative substrate binding site [chemical binding]"
                     /db_xref="CDD:176893"
     Site            order(217,222,372)
                     /site_type="other"
                     /note="Fe binding site [ion binding]"
                     /db_xref="CDD:176893"
ORIGIN      
        1 mdvtstlslg dpleparkat admlrsrdhs fslpqpfycd qrlfeidmqe ifhkewliag
       61 mtceipakgn fltlqigknp vlvirgaegq vhafhnvcrh rgsrlcvsek gkvaklvcpy
      121 hqwtyeldgr llfagtemga dfdmkeyglk piqvktaggy ifislaenpp aiddflatle
      181 hymepydmen akvavqttir eaanwklvie nnrecyhcng shpellktll ewddvtdpra
      241 sqafkdqvaa ctsawdaeki pyahasfglr nrivrmplld gtvsmtmdgk qgskklmgri
      301 knpdlgsmri lhlphswnhc mgdhlivftv wpisaqetlv ttkwlvhkda vegvdydvar
      361 lrevwdatnd qdrrlaeenq rginsdayqp gpysktyefg vinfldwyse rmlnnlgees
      421 ahvrkvags