MULTISPECIES: 3-keto-5-aminohexanoate cleavage protein

LOCUS       WP_003096716             294 aa            linear   BCT 31-DEC-2024
            [Pseudomonas].
ACCESSION   WP_003096716
VERSION     WP_003096716.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 294)
  AUTHORS   Bastard,K., Smith,A.A., Vergne-Vaxelaire,C., Perret,A.,
            Zaparucha,A., De Melo-Minardi,R., Mariage,A., Boutard,M.,
            Debard,A., Lechaplais,C., Pelle,C., Pellouin,V., Perchat,N.,
            Petit,J.L., Kreimeyer,A., Medigue,C., Weissenbach,J.,
            Artiguenave,F., De Berardinis,V., Vallenet,D. and Salanoubat,M.
  TITLE     Revealing the hidden functional diversity of an enzyme family
  JOURNAL   Nat Chem Biol 10 (1), 42-49 (2014)
   PUBMED   24240508
REFERENCE   2  (residues 1 to 294)
  AUTHORS   Bellinzoni,M., Bastard,K., Perret,A., Zaparucha,A., Perchat,N.,
            Vergne,C., Wagner,T., de Melo-Minardi,R.C., Artiguenave,F.,
            Cohen,G.N., Weissenbach,J., Salanoubat,M. and Alzari,P.M.
  TITLE     3-Keto-5-aminohexanoate cleavage enzyme: a common fold for an
            uncommon Claisen-type condensation
  JOURNAL   J Biol Chem 286 (31), 27399-27405 (2011)
   PUBMED   21632536
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10007120
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..294
                     /product="3-keto-5-aminohexanoate cleavage protein"
                     /EC_number="2.3.1.247"
                     /GO_function="GO:0043720 - 3-keto-5-aminohexanoate
                     cleavage activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0019475 - L-lysine catabolic process to
                     acetate [Evidence IEA]"
                     /calculated_mol_wt=31398
     Region          2..294
                     /region_name="COG3246"
                     /note="Uncharacterized conserved protein, DUF849 family
                     [Function unknown]"
                     /db_xref="CDD:442477"
ORIGIN      
        1 mnhevivtca vtgagdtvgr hpaipvtpkq iaeaaieaar agatvahchv rdpatgkpsr
       61 dvalyrevve riresdtdvi inltagmggd leigkgeqpl efgagtdlvg plerlrhvee
      121 llpeictldc gtlnfgdgdy iyvstpaqlr agarritelg vkaeleifdt ghlwfakqml
      181 keglledplf qiclgipwga padtttmkam adnlppgatw agfgigrtqm pmvaqamllg
      241 gnvrvgledn iwldkgvpas ngslveraie iierlggral spaegrrrmn lkpr