MULTISPECIES: two-component system sensor histidine kinase AmgS

LOCUS       WP_003096258             439 aa            linear   BCT 20-NOV-2023
            [Pseudomonas].
ACCESSION   WP_003096258
VERSION     WP_003096258.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 439)
  AUTHORS   Lau,C.H., Krahn,T., Gilmour,C., Mullen,E. and Poole,K.
  TITLE     AmgRS-mediated envelope stress-inducible expression of the mexXY
            multidrug efflux operon of Pseudomonas aeruginosa
  JOURNAL   Microbiologyopen 4 (1), 121-135 (2015)
   PUBMED   25450797
REFERENCE   2  (residues 1 to 439)
  AUTHORS   Lau,C.H., Fraud,S., Jones,M., Peterson,S.N. and Poole,K.
  TITLE     Mutational activation of the AmgRS two-component system in
            aminoglycoside-resistant Pseudomonas aeruginosa
  JOURNAL   Antimicrob Agents Chemother 57 (5), 2243-2251 (2013)
   PUBMED   23459488
REFERENCE   3  (residues 1 to 439)
  AUTHORS   Lee,S., Hinz,A., Bauerle,E., Angermeyer,A., Juhaszova,K.,
            Kaneko,Y., Singh,P.K. and Manoil,C.
  TITLE     Targeting a bacterial stress response to enhance antibiotic action
  JOURNAL   Proc Natl Acad Sci U S A 106 (34), 14570-14575 (2009)
   PUBMED   19706543
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            regulatory system involved in aminoglycoside resistance.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR013068
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..439
                     /gene="amgS"
     Protein         1..439
                     /product="two-component system sensor histidine kinase
                     AmgS"
                     /calculated_mol_wt=48700
     Region          7..427
                     /region_name="envZ"
                     /note="osmolarity sensor protein; Provisional; PRK09467"
                     /db_xref="CDD:236531"
ORIGIN      
        1 mktplwfpqs ffartlwlvl ivvlfskalt lvyllmnedv ivdrqyshga altirafwaa
       61 deesraaiak asglrwvpss adqpgeqhwp yteifqrqmq melgpdtetr lrihqpsqlw
      121 vrapslgegw lavplyphpl rgqriwsvlg wflgigllst aaawifvrql sqplkrlvva
      181 arqfgqgrsv rlplgpetps emaevyrafn qmaedieqgg rerelmlagv shdlrtpltr
      241 lrlslellpe seremvedmi rdiedmdail dqflafirdg rdepveegdl tdlvrevvap
      301 fnqtreqvrm alqpvpampl rrvsmkrllg nlidnalnhg ggsvevasyv agesaapyvv
      361 lsvldrgqgi dpaevdsifn pfirgdkarg gkgtglglai vkriaaqhgg svelrnrdgg
      421 glearvclpl glllprgaa