MULTISPECIES: imidazoleglycerol-phosphate dehydratase HisB

LOCUS       WP_003096088             197 aa            linear   BCT 20-NOV-2023
            [Pseudomonas].
ACCESSION   WP_003096088
VERSION     WP_003096088.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002106.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00951
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..197
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..197
                     /gene="hisB"
     Protein         1..197
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /EC_number="4.2.1.19"
                     /GO_function="GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=21806
     Region          2..197
                     /region_name="hisB"
                     /note="imidazoleglycerol-phosphate dehydratase HisB;
                     PRK00951"
                     /db_xref="CDD:234873"
     Site            order(14,40,44,47..48,66..67,70,92,100..101,114,138,
                     162..163,166)
                     /site_type="active"
                     /note="putative active site pocket [active]"
                     /db_xref="CDD:153419"
     Site            order(36..37,40,62..64,66..67,125..129,132,134,137..138,
                     159..163)
                     /site_type="other"
                     /note="4-fold oligomerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:153419"
     Site            order(40,66..67,70,138,162..163,166)
                     /site_type="metal-binding"
                     /note="metal binding residues [ion binding]"
                     /db_xref="CDD:153419"
     Site            order(91,93,95..97,99..101,103..104,108..110,114,116,150,
                     152,154,156,174,177,183)
                     /site_type="other"
                     /note="3-fold/trimer interface [polypeptide binding]"
                     /db_xref="CDD:153419"
ORIGIN      
        1 maerkasvar dtletqikvs idldgtgkar fdtgvpfldh mmdqiarhgl idldieckgd
       61 lhiddhhtve digitlgqaf akaigdkkgi rryghayvpl dealsrvvid fsgrpglqmh
      121 vpftrasvgg fdvdlfmeff qgfvnhaqvt lhidnlrghn thhqietvfk afgralrmai
      181 eldermagqm pstkgcl