MULTISPECIES: MFS transporter [Pseudomonas].

LOCUS       WP_003095819             438 aa            linear   BCT 22-JUL-2024
ACCESSION   WP_003095819
VERSION     WP_003095819.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 438)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 438)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023516
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..438
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=46644
     Region          50..409
                     /region_name="MFS_NepI_like"
                     /note="Purine ribonucleoside efflux pump NepI and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17324"
                     /db_xref="CDD:340882"
     Site            order(59..60,63..64,67,99,149..150,152..154,157,177,
                     180..181,184,258,261..262,265..267,270,298,302,350..351,
                     355,359,374,377..378,381..382,385)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340882"
ORIGIN      
        1 msnpqvrpqa eeepalieaa reaanevlea ateveryiek gtpqfmrtsl alfsggfatf
       61 allyciqpmm pvlskafsis aaesslalsv atamlalgll vtgpisdaig rkpvmvvsll
      121 aaalftlgsa vmptwhgvll mralvglsls glaavamtyl seeihpqhig lsmglyiggn
      181 aiggmsgrli sgvlvdfisw haalavlggl alvaalvfwr vlpeskhfrp aplkpatlln
      241 gyrlhfrdag lpwlfligfl lmgsfvtlfn yigyrllaep yhmsqavvgv lsvvylsgiy
      301 ssawvgslad klgrrkvlwa villmlggll ltlfepiplm laglllftfg ffgahsvass
      361 wigrralrak gqasslylfs yyvgsslagt lggvfwhyyg wngiglfigs llvvavlvsl
      421 hlarlpalpg ntlaqpah