MULTISPECIES: LysR family transcriptional regulator [Pseudomonas].

LOCUS       WP_003095545             298 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003095545
VERSION     WP_003095545.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 298)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 298)
  AUTHORS   Felder,C.B., Graul,R.C., Lee,A.Y., Merkle,H.P. and Sadee,W.
  TITLE     The Venus flytrap of periplasmic binding proteins: an ancient
            protein module present in multiple drug receptors
  JOURNAL   AAPS PharmSci 1 (2), E2 (1999)
   PUBMED   11741199
REFERENCE   3  (residues 1 to 298)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444097
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..298
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /calculated_mol_wt=33415
     Region          6..61
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          96..292
                     /region_name="PBP2_DntR_NahR_LinR_like"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulators that are involved in
                     the catabolism of dinitrotoluene, naphthalene and
                     gamma-hexachlorohexane; contains the type 2 periplasmic
                     binding fold; cd08459"
                     /db_xref="CDD:176148"
     Site            order(102,104..105,109,165,201,268)
                     /site_type="other"
                     /note="substrate binding pocket [chemical binding]"
                     /db_xref="CDD:176148"
     Site            order(103,106..107,110..111,114..115,117..118,121..122,
                     124..128,130,191,218..222,225..226,229..230,233,247)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:176148"
ORIGIN      
        1 mspidlnlir tfvtlyeags vtlaaerlfv tqpsvsyala rlrelfddal ftrtrdgiqp
       61 tfvaeqlygt fresltrieg avqsvrhfdp atterrfria ltdlgevgfl slilerltrd
      121 apfaevevlp lqvdevgawl ssakvdaaic rqpvpgarsq rvlheryvcl lsdrhprigd
      181 slsleqylae rhivvtrtsg hgiaedvlea mqvqrrislr vphfsvlpki ipgtelltil
      241 paqiayrfva eggmrmlelp ftlppfdvsl hwhessersa alnwfrttia eaiiaaqr