MULTISPECIES: MFS transporter [Pseudomonas].

LOCUS       WP_003095519             438 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003095519
VERSION     WP_003095519.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 438)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 438)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 438)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   4  (residues 1 to 438)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024677
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..438
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=47323
     Region          11..371
                     /region_name="MFS_YcaD_like"
                     /note="YcaD and similar transporters of the Major
                     Facilitator Superfamily; cd17477"
                     /db_xref="CDD:341030"
     Site            order(18..19,22..23,26,58,108..109,111..113,116,136,
                     139..140,143,210,213..214,217..219,222,246,250,301..302,
                     306,310,326,329..330,333..334,337)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:341030"
ORIGIN      
        1 mfsplvtfpa lytatllmla gsglfttyig lrltqegagd lwvgglmasy yfglvcggkf
       61 ghkliasfgh irsyvacagi atvtvllhal vdqlevwlll rfitgavmmn qymvieswln
      121 eqaeshqrgk vfagymvavd lglvlgqgll alsptldykp lllvaicfas cliplamtrr
      181 vhpaklvaap levrffwqrv pqalgtifia glmvgafygl apvyanrngl dasqssffvg
      241 mcivagfcaq wplgwlsdrl drswlirgna vllclasipm wglvtlpywl llangfvtgm
      301 llftlyplav alandhveqp rrvalsamll ttygvgacig plvagalmrh fgpglfymlv
      361 sgyavllvfw vqpkrvtgeh rvdeaplqhv ampdtvspma atldprveev peelvveapa
      421 nigrsdgepd agekpaqs