MULTISPECIES: Cu(I)-responsive transcriptional regulator

LOCUS       WP_003095248             132 aa            linear   BCT 09-DEC-2024
            [Pseudomonas].
ACCESSION   WP_003095248
VERSION     WP_003095248.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 132)
  AUTHORS   Changela,A., Chen,K., Xue,Y., Holschen,J., Outten,C.E.,
            O'Halloran,T.V. and Mondragon,A.
  TITLE     Molecular basis of metal-ion selectivity and zeptomolar sensitivity
            by CueR
  JOURNAL   Science 301 (5638), 1383-1387 (2003)
   PUBMED   12958362
REFERENCE   2  (residues 1 to 132)
  AUTHORS   Stoyanov,J.V., Hobman,J.L. and Brown,N.L.
  TITLE     CueR (YbbI) of Escherichia coli is a MerR family regulator
            controlling expression of the copper exporter CopA
  JOURNAL   Mol Microbiol 39 (2), 502-511 (2001)
   PUBMED   11136469
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02044.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..132
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..132
                     /gene="cueR"
     Protein         1..132
                     /product="Cu(I)-responsive transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0045893 - positive regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /GO_process="GO:0046688 - response to copper ion [Evidence
                     IEA]"
                     /calculated_mol_wt=14884
     Region          1..127
                     /region_name="HTH_CueR"
                     /note="Helix-Turn-Helix DNA binding domain of CueR-like
                     transcription regulators; cd01108"
                     /db_xref="CDD:133383"
     Site            order(2..4,18,35..37)
                     /site_type="DNA binding"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:133383"
     Site            order(49,52,56..57,66,70,77..78,81,84,88,94,98,101..102,
                     109,114..118,120,122,125..126)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:133383"
     Site            order(77,112,120)
                     /site_type="other"
                     /note="copper binding site [ion binding]"
                     /db_xref="CDD:133383"
ORIGIN      
        1 mnigeaakks gltpkmiryy esiellrpag rsasgyrhyn endlhtlafi rrsrdlgfsl
       61 devgklltlw qdrqrasadv kalaaqhvre lnrkieelst lrdtlqdlve hcqgdhrpdc
      121 pilkdlasgc ch