MULTISPECIES: glutamine-hydrolyzing carbamoyl-phosphate synthase

LOCUS       WP_003095209             378 aa            linear   BCT 04-JUN-2024
            small subunit [Pseudomonas].
ACCESSION   WP_003095209
VERSION     WP_003095209.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 378)
  AUTHORS   Thoden,J.B., Huang,X., Kim,J., Raushel,F.M. and Holden,H.M.
  TITLE     Long-range allosteric transitions in carbamoyl phosphate synthetase
  JOURNAL   Protein Sci 13 (9), 2398-2405 (2004)
   PUBMED   15322282
REFERENCE   2  (residues 1 to 378)
  AUTHORS   Miles,B.W., Thoden,J.B., Holden,H.M. and Raushel,F.M.
  TITLE     Inactivation of the amidotransferase activity of carbamoyl
            phosphate synthetase by the antibiotic acivicin
  JOURNAL   J Biol Chem 277 (6), 4368-4373 (2002)
   PUBMED   11729189
REFERENCE   3  (residues 1 to 378)
  AUTHORS   Thoden,J.B., Raushel,F.M., Benning,M.M., Rayment,I. and Holden,H.M.
  TITLE     The structure of carbamoyl phosphate synthetase determined to 2.1 A
            resolution
  JOURNAL   Acta Crystallogr D Biol Crystallogr 55 (Pt 1), 8-24 (1999)
   PUBMED   10089390
REFERENCE   4  (residues 1 to 378)
  AUTHORS   Thoden,J.B., Holden,H.M., Wesenberg,G., Raushel,F.M. and Rayment,I.
  TITLE     Structure of carbamoyl phosphate synthetase: a journey of 96 A from
            substrate to product
  JOURNAL   Biochemistry 36 (21), 6305-6316 (1997)
   PUBMED   9174345
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01368.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..378
                     /gene="carA"
     Protein         1..378
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /EC_number="6.3.5.5"
                     /GO_function="GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=40697
     Region          1..375
                     /region_name="CarA"
                     /note="Carbamoylphosphate synthase small subunit [Amino
                     acid transport and metabolism, Nucleotide transport and
                     metabolism]; COG0505"
                     /db_xref="CDD:440271"
ORIGIN      
        1 mtkpailala dgsifrgeai gadgqtvgev vfntamtgyq eiltdpsyaq qivtltyphi
       61 gntgttpeda eanrvwaagl iirdlplias nwrskqslpd ylkangtvai agidtrrltr
      121 ilrekgsqng cilagadate eralelaraf pglkgmdlak evttaeryew rssvwnlesd
      181 shpeipagel pyhvvaydyg vklnilrmlv argcrltvvp aqtpasevla lnpdgiflsn
      241 gpgdpepcdy aiqairefld teipvfgicl ghqllalasg aktlkmghgh hganhpvqdl
      301 dsgvvmitsq nhgfavdest lpdnlrathk slfdgtlqgi ertdkvafsf qghpeaspgp
      361 hdvaplfdrf isamaerr