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MULTISPECIES: MerR family transcriptional regulator [Pseudomonas].


LOCUS       WP_003094990             299 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003094990
VERSION     WP_003094990.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 299)
  AUTHORS   Fang,C. and Zhang,Y.
  TITLE     Bacterial MerR family transcription regulators: activationby
            distortion
  JOURNAL   Acta Biochim Biophys Sin (Shanghai) 54 (1), 25-36 (2022)
   PUBMED   35130613
REFERENCE   2  (residues 1 to 299)
  AUTHORS   Hobman,J.L.
  TITLE     MerR family transcription activators: similar designs, different
            specificities
  JOURNAL   Mol Microbiol 63 (5), 1275-1278 (2007)
   PUBMED   17302809
REFERENCE   3  (residues 1 to 299)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   4  (residues 1 to 299)
  AUTHORS   Brown,N.L., Stoyanov,J.V., Kidd,S.P. and Hobman,J.L.
  TITLE     The MerR family of transcriptional regulators
  JOURNAL   FEMS Microbiol Rev 27 (2-3), 145-163 (2003)
   PUBMED   12829265
REFERENCE   5  (residues 1 to 299)
  AUTHORS   Rosinski,J.A. and Atchley,W.R.
  TITLE     Molecular evolution of helix-turn-helix proteins
  JOURNAL   J Mol Evol 49 (3), 301-309 (1999)
   PUBMED   10473770
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11542020
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..299
                     /product="MerR family transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=33828
     Region          11..78
                     /region_name="HTH_MlrA-CarA"
                     /note="Helix-Turn-Helix DNA binding domain of the
                     transcription regulators MlrA and CarA; cd01104"
                     /db_xref="CDD:133379"
     Site            order(12..14,28,45..47)
                     /site_type="DNA binding"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:133379"
     Region          13..>146
                     /region_name="PRK15043"
                     /note="HTH-type transcriptional regulator MlrA"
                     /db_xref="CDD:185003"
ORIGIN      
        1 mnsphlergg lpirevtrlt gvhpvtlraw erryglvvpq rtgkghrlys eeqverirri
       61 lvwlergvai sqvrallerp eetpaadves pwerlheqll daiaalaerr lddlfnqaas
      121 lypvatlcek llqpllqhle rrwqgqfgar merafffswl rsklgarlyh qqrlqqgapl
      181 llvnqselsl epnlwlcswl lgsgevplqv fdwplppael alacerlear gvllyashrl
      241 npehlprlla gvscpvvlvg paveiqreaf etlaltglll astplearrl lgergllnp