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LOCUS WP_003094423 236 aa linear BCT 02-MAR-2025 ACCESSION WP_003094423 VERSION WP_003094423.1 KEYWORDS RefSeq. SOURCE Pseudomonas ORGANISM Pseudomonas Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae. REFERENCE 1 (residues 1 to 236) AUTHORS Vig,E., Green,M., Liu,Y., Yu,K.Y., Kwon,H.J., Tian,J., Goebl,M.G. and Harrington,M.A. TITLE SIMPL is a tumor necrosis factor-specific regulator of nuclear factor-kappaB activity JOURNAL J Biol Chem 276 (11), 7859-7866 (2001) PUBMED 11096118 REFERENCE 2 (residues 1 to 236) AUTHORS Pfeuffer,T., Goebel,W., Laubinger,J., Bachmann,M. and Kuhn,M. TITLE LaXp180, a mammalian ActA-binding protein, identified with the yeast two-hybrid system, co-localizes with intracellular Listeria monocytogenes JOURNAL Cell Microbiol 2 (2), 101-114 (2000) PUBMED 11207567 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF016300.6 Evidence Source :: EMBL-EBI Source Identifier :: PF04402.19 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..236 /organism="Pseudomonas" /db_xref="taxon:286" Protein 1..236 /product="SIMPL domain-containing protein" /note="The SIMPL domain is named for its presence in mouse protein SIMPL (signalling molecule that associates with mouse pelle-like kinase). Bacterial member BP26, from Brucella, was shown to assemble into a channel-like structure, while YggE from E. coli has been associated with resistance to oxidative stress.; The SIMPL domain is named for its presence in mouse protein SIMPL (signalling molecule that associates with mouse pelle-like kinase). Bacterial member BP26, from Brucella, was shown to assemble into a channel-like structure, while YggE from E. coli has been associated with resistance to oxidative stress.; The SIMPL domain is named for its presence in mouse protein SIMPL (signalling molecule that associates with mouse pelle-like kinase). Bacterial member BP26, from Brucella, was shown to assemble into a channel-like structure, while YggE from E. coli has been associated with resistance to oxidative stress.; The SIMPL domain is named for its presence in mouse protein SIMPL (signalling molecule that associates with mouse pelle-like kinase). Bacterial member BP26, from Brucella, was shown to assemble into a channel-like structure, while YggE from E. coli has been associated with resistance to oxidative stress." /calculated_mol_wt=24748 Region 1..234 /region_name="COG3471" /note="Predicted secreted (periplasmic) protein [Function unknown]" /db_xref="CDD:442694" ORIGIN 1 msaisrlaaa vtlcaaslsa vaeeaprynq vslhaevsqq vahdlmqvtl ysenqgsdpa 61 klaaettsvl naavadarkv kgvtislgsr nsypvyddkg qkitgwrera elrlessdfa 121 algqlsadll gklkmggmdf siadatrkkn edqlmkgavd afkeraqllt ealggkgykl 181 vslsvnsaga prpypvmrma amkadasfgg aqapeieagt sqvtvnadgv ievqmp