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MULTISPECIES: MlaC/ttg2D family ABC transporter substrate-binding


LOCUS       WP_003094337             215 aa            linear   BCT 17-FEB-2025
            protein [Pseudomonas].
ACCESSION   WP_003094337
VERSION     WP_003094337.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 215)
  AUTHORS   Yero,D., Diaz-Lobo,M., Costenaro,L., Conchillo-Sole,O., Mayo,A.,
            Ferrer-Navarro,M., Vilaseca,M., Gibert,I. and Daura,X.
  TITLE     The Pseudomonas aeruginosa substrate-binding protein Ttg2D
            functions as a general glycerophospholipid transporter across the
            periplasm
  JOURNAL   Commun Biol 4 (1), 448 (2021)
   PUBMED   33837253
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 215)
  AUTHORS   Ekiert,D.C., Bhabha,G., Isom,G.L., Greenan,G., Ovchinnikov,S.,
            Henderson,I.R., Cox,J.S. and Vale,R.D.
  TITLE     Architectures of Lipid Transport Systems for the Bacterial Outer
            Membrane
  JOURNAL   Cell 169 (2), 273-285 (2017)
   PUBMED   28388411
REFERENCE   3  (residues 1 to 215)
  AUTHORS   Maqbool,A., Horler,R.S., Muller,A., Wilkinson,A.J., Wilson,K.S. and
            Thomas,G.H.
  TITLE     The substrate-binding protein in bacterial ABC transporters:
            dissecting roles in the evolution of substrate specificity
  JOURNAL   Biochem Soc Trans 43 (5), 1011-1017 (2015)
   PUBMED   26517916
REFERENCE   4  (residues 1 to 215)
  AUTHORS   Wilkens,S.
  TITLE     Structure and mechanism of ABC transporters
  JOURNAL   F1000Prime Rep 7, 14 (2015)
   PUBMED   25750732
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 215)
  AUTHORS   ter Beek,J., Guskov,A. and Slotboom,D.J.
  TITLE     Structural diversity of ABC transporters
  JOURNAL   J Gen Physiol 143 (4), 419-435 (2014)
   PUBMED   24638992
REFERENCE   6  (residues 1 to 215)
  AUTHORS   Malinverni,J.C. and Silhavy,T.J.
  TITLE     An ABC transport system that maintains lipid asymmetry in the
            gram-negative outer membrane
  JOURNAL   Proc Natl Acad Sci U S A 106 (19), 8009-8014 (2009)
   PUBMED   19383799
REFERENCE   7  (residues 1 to 215)
  AUTHORS   Locher,K.P.
  TITLE     Structure and mechanism of ABC transporters
  JOURNAL   Curr Opin Struct Biol 14 (4), 426-431 (2004)
   PUBMED   15313236
REFERENCE   8  (residues 1 to 215)
  AUTHORS   Tam,R. and Saier,M.H. Jr.
  TITLE     Structural, functional, and evolutionary relationships among
            extracellular solute-binding receptors of bacteria
  JOURNAL   Microbiol Rev 57 (2), 320-346 (1993)
   PUBMED   8336670
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10006734
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..215
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..215
                     /product="MlaC/ttg2D family ABC transporter
                     substrate-binding protein"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /calculated_mol_wt=23629
     Region          24..207
                     /region_name="MlaC"
                     /note="Periplasmic subunit MlaC of the ABC-type
                     intermembrane phospholipid transporter Mla [Cell
                     wall/membrane/envelope biogenesis]; COG2854"
                     /db_xref="CDD:442102"
ORIGIN      
        1 mltllrrgll vflaafplls maaptpqqvv qgtvdellsd ikankaayka dpqklyatld
       61 rilgpvvdae giaksvmtvk ysrqaspeqi krfeevfkns lmqfygnall eydnqdirvl
      121 pssakpsddr asvnmeirds kgtvypvsyt mtnlaggwkv rnviingini gklfrdqfad
      181 tmqknrndle ktiagwgevv akaketakae eagak