MULTISPECIES: NADP(H)-dependent aldo-keto reductase [Pseudomonas].

LOCUS       WP_003094166             345 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003094166
VERSION     WP_003094166.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 345)
  AUTHORS   Obmolova,G., Teplyakov,A., Khil,P.P., Howard,A.J.,
            Camerini-Otero,R.D. and Gilliland,G.L.
  TITLE     Crystal structure of the Escherichia coli Tas protein, an
            NADP(H)-dependent aldo-keto reductase
  JOURNAL   Proteins 53 (2), 323-325 (2003)
   PUBMED   14517983
REFERENCE   2  (residues 1 to 345)
  AUTHORS   Johnson,J.M. 3rd, Ding,W., Henkhaus,J. and Fix,D.
  TITLE     Identification of a mutation causing increased expression of the
            tas gene in Escherichia coli FX-11
  JOURNAL   Mutat. Res. 479 (1-2), 121-130 (2001)
   PUBMED   11470487
REFERENCE   3  (residues 1 to 345)
  AUTHORS   Timms,A.R. and Bridges,B.A.
  TITLE     Reversion of the tyrosine ochre strain Escherichia coli WU3610
            under starvation conditions depends on a new gene tas
  JOURNAL   Genetics 148 (4), 1627-1635 (1998)
   PUBMED   9560382
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007912.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10625
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..345
                     /product="NADP(H)-dependent aldo-keto reductase"
                     /GO_function="GO:0047834 - D-threo-aldose 1-dehydrogenase
                     activity [Evidence IEA]"
                     /calculated_mol_wt=38514
     Region          13..336
                     /region_name="AKR_Tas-like"
                     /note="Escherichia coli Tas protein and similar proteins;
                     cd19094"
                     /db_xref="CDD:381320"
     Site            order(19..21,26,48,53,87,132,178..179,204,232..238,241,
                     243,252..254,288,305..309,313,317)
                     /site_type="active"
                     /db_xref="CDD:381320"
     Site            order(48,53,87,132)
                     /site_type="active"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:381320"
ORIGIN      
        1 meyrplgrtd lkvsalclgt mtwgeqnseq dafaqiarak aaginfmdta emypvpprae
       61 tyasteriig nwfrrsgdra dwilaskiag pgngishvrd gnlkfnrqhi vaaldasler
      121 lqtdwldlyq lhwperrtnf fgqlgyqhqe esftpleetl evldeqvrag kirhiglsne
      181 tpwgtmtflr laeergwpra vsiqnpynll nrsfevglae iaireqcgll ayspmafgml
      241 sgkyadgarp anarislysr ftrytnpqae aacaryvala rehglepaqm alayvtsrpf
      301 vtsniigats leqletnlgs vdlrldeevl agidaihreq pnpap