MULTISPECIES: phenazine biosynthesis protein PhzD

LOCUS       WP_003093625             207 aa            linear   BCT 07-AUG-2024
            [Gammaproteobacteria].
ACCESSION   WP_003093625
VERSION     WP_003093625.1
KEYWORDS    RefSeq.
SOURCE      Gammaproteobacteria
  ORGANISM  Gammaproteobacteria
            Bacteria; Pseudomonadati; Pseudomonadota.
REFERENCE   1  (residues 1 to 207)
  AUTHORS   Recinos,D.A., Sekedat,M.D., Hernandez,A., Cohen,T.S., Sakhtah,H.,
            Prince,A.S., Price-Whelan,A. and Dietrich,L.E.
  TITLE     Redundant phenazine operons in Pseudomonas aeruginosa exhibit
            environment-dependent expression and differential roles in
            pathogenicity
  JOURNAL   Proc Natl Acad Sci U S A 109 (47), 19420-19425 (2012)
   PUBMED   23129634
REFERENCE   2  (residues 1 to 207)
  AUTHORS   Chen,L., Yang,J., Yu,J., Yao,Z., Sun,L., Shen,Y. and Jin,Q.
  TITLE     VFDB: a reference database for bacterial virulence factors
  JOURNAL   Nucleic Acids Res 33 (Database issue), D325-D328 (2005)
   PUBMED   15608208
REFERENCE   3  (residues 1 to 207)
  AUTHORS   Parsons,J.F., Calabrese,K., Eisenstein,E. and Ladner,J.E.
  TITLE     Structure and mechanism of Pseudomonas aeruginosa PhzD, an
            isochorismatase from the phenazine biosynthetic pathway
  JOURNAL   Biochemistry 42 (19), 5684-5693 (2003)
   PUBMED   12741825
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR012830
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..207
                     /organism="Gammaproteobacteria"
                     /db_xref="taxon:1236"
     gene            1..207
                     /gene="phzD"
     Protein         1..207
                     /product="phenazine biosynthesis protein PhzD"
                     /calculated_mol_wt=23065
     Region          3..203
                     /region_name="isochorismatase"
                     /note="Isochorismatase, also known as 2,3 dihydro-2,3
                     dihydroxybenzoate synthase, catalyses the conversion of
                     isochorismate, in the presence of water, to
                     2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of
                     a vinyl ether, an uncommon reaction in biological...;
                     cd01013"
                     /db_xref="CDD:238495"
     Site            order(4,43,94,125,151,154,180)
                     /site_type="active"
                     /note="hydrophobic substrate binding pocket [active]"
                     /db_xref="CDD:238495"
     Site            order(38,78,87,122,151,155)
                     /site_type="active"
                     /db_xref="CDD:238495"
     Site            150..151
                     /site_type="active"
                     /note="conserved cis-peptide bond [active]"
                     /db_xref="CDD:238495"
ORIGIN      
        1 msgipeitay plptaqqlpa nlarwslepr ravllvhdmq ryflrplpes lraglvanaa
       61 rlrrwcveqg vqiaytaqpg smteeqrgll kdfwgpgmra spadrevvee lapgpddwll
      121 tkwrysaffh sdllqrmraa grdqlvlcgv yahvgvlist vdaysndiqp flvadaiadf
      181 seahhrmale yaasrcamvv ttdevle