MULTISPECIES: NAD-dependent epimerase/dehydratase family protein

LOCUS       WP_003093339             309 aa            linear   BCT 01-MAR-2025
            [Pseudomonas].
ACCESSION   WP_003093339
VERSION     WP_003093339.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 309)
  AUTHORS   Thoden,J.B., Hegeman,A.D., Wesenberg,G., Chapeau,M.C., Frey,P.A.
            and Holden,H.M.
  TITLE     Structural analysis of UDP-sugar binding to UDP-galactose
            4-epimerase from Escherichia coli
  JOURNAL   Biochemistry 36 (21), 6294-6304 (1997)
   PUBMED   9174344
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF013530.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF01370.27
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..309
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /calculated_mol_wt=33180
     Region          6..307
                     /region_name="Rossmann-fold NAD(P)(+)-binding proteins"
                     /note="A large family of proteins that share a
                     Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The
                     NADB domain is found in numerous dehydrogenases of
                     metabolic pathways such as glycolysis, and many other
                     redox enzymes. NAD binding involves numerous...; cl21454"
                     /db_xref="CDD:473865"
     Site            order(10,12..13,15,34..36,77..79,119..121,146,150,
                     173..176)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:187566"
     Site            order(97,121,146,150)
                     /site_type="active"
                     /db_xref="CDD:187566"
ORIGIN      
        1 mferpilitg gagfigshlt dallargyrv rvldnlstgk rdnlpldder vellegdaad
       61 aatlaaalkg caavahlaav asvqasvddp vathqsnfia tlnlceamre qgvkrvvfas
      121 saavygqnge gtaidedtpk spltpyasdk laseyyldfy rrqhglepai frffnvygpr
      181 qdpsspysgv isifteralk gtpitvfgdg eqtrdfiyva dlvdflvqal eatavepgav
      241 nvglnrsisl kqllaeigqv lgglppvtha daragdirhs rannerllrr frfdqptpmg
      301 vglarllgr