MULTISPECIES: IMP dehydrogenase [Pseudomonas].

LOCUS       WP_003092702             489 aa            linear   BCT 04-JUN-2024
ACCESSION   WP_003092702
VERSION     WP_003092702.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 489)
  AUTHORS   Alexandre,T., Raynal,B. and Munier-Lehmann,H.
  TITLE     Two classes of bacterial IMPDHs according to their quaternary
            structures and catalytic properties
  JOURNAL   PLoS One 10 (2), e0116578 (2015)
   PUBMED   25706619
  REMARK    Erratum:[PLoS One. 2015;10(4):e0125884. Rayna, Bertrand [corrected
            to Raynal, Bertrand]. PMID: 25923221]
            Publication Status: Online-Only
REFERENCE   2  (residues 1 to 489)
  AUTHORS   Pimkin,M. and Markham,G.D.
  TITLE     The CBS subdomain of inosine 5'-monophosphate dehydrogenase
            regulates purine nucleotide turnover
  JOURNAL   Mol Microbiol 68 (2), 342-359 (2008)
   PUBMED   18312263
REFERENCE   3  (residues 1 to 489)
  AUTHORS   Zhang,R., Evans,G., Rotella,F.J., Westbrook,E.M., Beno,D.,
            Huberman,E., Joachimiak,A. and Collart,F.R.
  TITLE     Characteristics and crystal structure of bacterial
            inosine-5'-monophosphate dehydrogenase
  JOURNAL   Biochemistry 38 (15), 4691-4700 (1999)
   PUBMED   10200156
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01302.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..489
                     /gene="guaB"
     Protein         1..489
                     /product="IMP dehydrogenase"
                     /EC_number="1.1.1.205"
                     /GO_function="GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=51577
     Region          8..475
                     /region_name="IMPDH"
                     /note="IMP dehydrogenase / GMP reductase domain;
                     pfam00478"
                     /db_xref="CDD:459826"
ORIGIN      
        1 mlrisqealt fddvllipgy sevlpkdvsl ktrltrgiel niplvsaamd tvtearlaia
       61 maqeggigii hknmgieqqa aevrkvkkhe taivrdpvtv tpstkiiell qmareygfsg
      121 fpvveqgelv givtgrdlrv kpnagdtvaa imtpkdklvt aregtpleem kaklyenrie
      181 kmlvvdenfy lrglvtfrdi ekaktyplas kdeqgrlrvg aavgtgadtg ervaalvaag
      241 vdvvvvdtah ghskgvierv rwvkqtfpdv qviggniata eaakalaeag adavkvgigp
      301 gsicttriva gvgvpqisai anvaaalegt gvpliadggi rfsgdlakam vagaycvmmg
      361 smfagteeap geielfqgrs yksyrgmgsl gamsgsqgss dryfqdasag aeklvpegie
      421 grvpykgals aivhqlmggl raamgytgsa diqqmrtqpq fvritgagma eshvhdvqit
      481 keapnyrvg