MULTISPECIES: S-(hydroxymethyl)glutathione dehydrogenase/class III

LOCUS       WP_003092351             370 aa            linear   BCT 06-NOV-2024
            alcohol dehydrogenase [Pseudomonas].
ACCESSION   WP_003092351
VERSION     WP_003092351.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02818.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..370
                     /product="S-(hydroxymethyl)glutathione dehydrogenase/class
                     III alcohol dehydrogenase"
                     /GO_function="GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051903 - S-(hydroxymethyl)glutathione
                     dehydrogenase [NAD(P)+] activity [Evidence IEA]"
                     /calculated_mol_wt=39077
     Region          2..369
                     /region_name="alcohol_DH_class_III"
                     /note="class III alcohol dehydrogenases; cd08300"
                     /db_xref="CDD:176260"
     Site            order(41,43,52..54,63,89..90,170,290,314)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:176260"
     Site            order(41,63..64,170)
                     /site_type="other"
                     /note="catalytic Zn binding site [ion binding]"
                     /db_xref="CDD:176260"
     Site            order(42..43,170,174,195..199,219..220,224,264..265,
                     269..270,288..289,313..315,365)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:176260"
     Site            order(93,96,99,107)
                     /site_type="other"
                     /note="structural Zn binding site [ion binding]"
                     /db_xref="CDD:176260"
     Site            order(97..98,101,103..104,106,108,255,260,271..272,
                     279..282,291,294..301,304..306,309..314)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:176260"
ORIGIN      
        1 miksraavaf apnkpleive vdvappqkge vlvrivatgv chtdaytlsg qdsegvfpci
       61 lghegggive avgegvtslq vgdhviplyt aecgkckfcl sgktnlcqav ratqgkglmp
      121 dgtsrfsykg epvfhymgcs tfseytvlpe islakipkda plekvcllgc gvttgigavl
      181 ntakveegat vaifglggig laaiigakma kaariiavdi npgkfdiare lgatdfinpk
      241 dydkpiqdvi veltdggvdy sfecvgnvql mraalecchk gwgesviigv agagqeistr
      301 pfqlvtgrvw rgsafggvrg rselpsyvek aqkgeipldt fithtmgled ineafelmhe
      361 gksirtvihy