MULTISPECIES: multidrug effflux MFS transporter [Pseudomonas].

LOCUS       WP_003092150             392 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003092150
VERSION     WP_003092150.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 392)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 392)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022939
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..392
                     /product="multidrug effflux MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=40812
     Region          6..382
                     /region_name="MFS_MdfA_MDR_like"
                     /note="Multidrug transporter MdfA and similar multidrug
                     resistance (MDR) transporters of the Major Facilitator
                     Superfamily; cd17320"
                     /db_xref="CDD:340878"
     Site            order(16..17,20..21,45,48..49,106,137,140..141,223,226,
                     345)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:340878"
ORIGIN      
        1 mnlrillilg alsafgplai dfylpsfptl akafatdveh vqlslaayfa glsigqllyg
       61 pvadrygrrl pllvgvsift lasaacalap slewliaarf vqalggcagm visravvrdl
      121 cdpigaakaf sqlmlvmgla pilapvaggl lldwqgwqsi fvcltlfaal aglgvalwlp
      181 etipadgerp plsgalgqyr rlfadrlfla yglsggvama gmfayiagsp yvfiqlygip
      241 aehygwlfgs naagfivmaq vnarllryrg pafwlrriiw gylacglall giaslqpatl
      301 wpllvplfgc vaslgciipn asacamagqg qhagsasalm gslqfsvaag asalvgvlhd
      361 gtaipmtlvi avcgavatll awqtgrlerq aa