MULTISPECIES: GTP cyclohydrolase I FolE [Pseudomonas].

LOCUS       WP_003091896             186 aa            linear   BCT 25-JUL-2024
ACCESSION   WP_003091896
VERSION     WP_003091896.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00063.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..186
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..186
                     /gene="folE"
     Protein         1..186
                     /product="GTP cyclohydrolase I FolE"
                     /EC_number="3.5.4.16"
                     /GO_function="GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA]"
                     /GO_process="GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=20702
     Region          1..185
                     /region_name="PRK12606"
                     /note="GTP cyclohydrolase I; Reviewed"
                     /db_xref="CDD:237149"
     Site            order(4..5,8,12,15..16,18,20,22,24..26,28..29,31,35,38,43,
                     54,56,60..63,65..68,70,72,76..77,80..81,83,85,92..93,95,
                     99..101,104,114..116,118,121,131,144..146,149..150,
                     155..156,158..160,162..164,169..170,173,175..177)
                     /site_type="other"
                     /note="homodecamer interface [polypeptide binding]"
                     /db_xref="CDD:238349"
     Site            order(31,34,75,77..78,97,99..100,104,115..117,144,146,150)
                     /site_type="active"
                     /db_xref="CDD:238349"
     Site            order(75,77..78,144,146)
                     /site_type="active"
                     /note="putative catalytic site residues [active]"
                     /db_xref="CDD:238349"
     Site            order(75,77..78,146)
                     /site_type="other"
                     /note="zinc binding site [ion binding]"
                     /db_xref="CDD:238349"
     Site            order(125,128,134,136,165..167,169..173)
                     /site_type="active"
                     /note="GTP-CH-I/GFRP interaction surface [active]"
                     /db_xref="CDD:238349"
ORIGIN      
        1 mnpalsqhyr eilvglgedp qreglldtpk raakamqylc hgygqtleei vngalfasdn
       61 demvivrdie lyslcehhll pfigkahvay iptgkvlgls kvarivdmfa rrlqiqenlt
      121 rqiaeavrqv tsaagvavvi eaqhmcmmmr gvekqnsqmf tsvmlgafrd snttrqeflq
      181 ligrsk