MULTISPECIES: 3-isopropylmalate dehydratase large subunit

LOCUS       WP_003091399             474 aa            linear   BCT 01-JUL-2024
            [Pseudomonas].
ACCESSION   WP_003091399
VERSION     WP_003091399.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00170.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..474
                     /gene="leuC"
     Protein         1..474
                     /product="3-isopropylmalate dehydratase large subunit"
                     /EC_number="4.2.1.33"
                     /GO_component="GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster
                     binding [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=50911
     Region          2..473
                     /region_name="PRK05478"
                     /note="3-isopropylmalate dehydratase large subunit"
                     /db_xref="CDD:235490"
     Site            order(34,37,134..135,418,437,442)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:153133"
     Site            order(136,353,414,417..418,436)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:153133"
ORIGIN      
        1 magktlydkl wdmhlvkqrd dgsaliyidr hilhevtspq afeglrlagr kpwridania
       61 tpdhnvpttr terkggiaai adevsrlqvq tldencddfg itefkmndvr qgivhvvgpe
      121 qgatlpgmtv vcgdshtsth gafgalahgi gtsevehvla tqclvakkmk nmlvkvegrl
      181 pagvtakdiv lavigrigta ggnghaiefa gsairdlsie grmticnmsi eagarvglva
      241 vdqktidyvk grpfapsaeq wdqavacwqg lvsdadarfd tvveldaaqi kpqvswgtsp
      301 emvlavdqnv pdparesdpi krgsieralk ymglrpnqai tdiqldrvfi gsctnsried
      361 lraaaevarg rkvaatikqa lvvpgsglvk eqaekegldr ifieagfewr epgcsmclam
      421 npdrlesgeh castsnrnfe grqgaggrth lvspamaaaa avngrfidvr ella