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MULTISPECIES: tRNA pseudouridine(38-40) synthase TruA


LOCUS       WP_003091390             285 aa            linear   BCT 23-MAY-2024
            [Pseudomonas].
ACCESSION   WP_003091390
VERSION     WP_003091390.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 285)
  AUTHORS   Hur,S. and Stroud,R.M.
  TITLE     How U38, 39, and 40 of many tRNAs become the targets for
            pseudouridylation by TruA
  JOURNAL   Mol Cell 26 (2), 189-203 (2007)
   PUBMED   17466622
REFERENCE   2  (residues 1 to 285)
  AUTHORS   Dong,X., Bessho,Y., Shibata,R., Nishimoto,M., Shirouzu,M.,
            Kuramitsu,S. and Yokoyama,S.
  TITLE     Crystal structure of tRNA pseudouridine synthase TruA from Thermus
            thermophilus HB8
  JOURNAL   RNA Biol 3 (3), 115-122 (2006)
   PUBMED   17114947
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00071.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..285
                     /gene="truA"
     Protein         1..285
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /EC_number="5.4.99.12"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis
                     [Evidence IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /calculated_mol_wt=31352
     Region          19..267
                     /region_name="TruA"
                     /note="tRNA U38,U39,U40 pseudouridine synthase TruA
                     [Translation, ribosomal structure and biogenesis];
                     COG0101"
                     /db_xref="CDD:439871"
ORIGIN      
        1 mndvvppaaa esaaagvsri algieykgsr yrgwqrqeag vpsvqealer alskvaaepv
       61 gvicagrtda avhasgqvvh fdtaverplk awvmgtnanl padisvtwar vmpahfharf
      121 samarryrya iyndpirpah laeevtwnhr pldigrmrea aqvlvgthdf tsfravqcqa
      181 kspvktmhhv rllehgrliv ldirgnaflh hmvrniagvl mtigagerpi ewakevlear
      241 drraggvtah pyglylvrve ypgefelper ylgphflsgl pdivg