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MULTISPECIES: Hcp family type VI secretion system effector


LOCUS       WP_003089495             165 aa            linear   BCT 19-FEB-2025
            [Pseudomonas].
ACCESSION   WP_003089495
VERSION     WP_003089495.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 165)
  AUTHORS   Howard,S.A., Furniss,R.C.D., Bonini,D., Amin,H., Paracuellos,P.,
            Zlotkin,D., Costa,T.R.D., Levy,A., Mavridou,D.A.I. and Filloux,A.
  TITLE     The Breadth and Molecular Basis of Hcp-Driven Type VI Secretion
            System Effector Delivery
  JOURNAL   mBio 12 (3), e0026221 (2021)
   PUBMED   34061601
REFERENCE   2  (residues 1 to 165)
  AUTHORS   Zhou,Y., Tao,J., Yu,H., Ni,J., Zeng,L., Teng,Q., Kim,K.S.,
            Zhao,G.P., Guo,X. and Yao,Y.
  TITLE     Hcp family proteins secreted via the type VI secretion system
            coordinately regulate Escherichia coli K1 interaction with human
            brain microvascular endothelial cells
  JOURNAL   Infect Immun 80 (3), 1243-1251 (2012)
   PUBMED   22184413
REFERENCE   3  (residues 1 to 165)
  AUTHORS   Cascales,E.
  TITLE     The type VI secretion toolkit
  JOURNAL   EMBO Rep 9 (8), 735-741 (2008)
   PUBMED   18617888
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10006986
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..165
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..165
                     /product="Hcp family type VI secretion system effector"
                     /GO_process="GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /calculated_mol_wt=17505
     Region          11..162
                     /region_name="Hcp"
                     /note="Type VI protein secretion system component Hcp
                     (secreted cytotoxin) [Intracellular trafficking,
                     secretion, and vesicular transport]; COG3157"
                     /db_xref="CDD:442391"
ORIGIN      
        1 mdaiildfgs dikgdsllvg yenkieimsy shnvamqvtn dvsnsertsg kphvgeftlt
       61 kfidtstptl neyccagkpi aeatitigrn aaegngqimp fivytlnnvv lsnvsvsgga
      121 ggkpvetlsl nftkikwelt aqkddgtkeg taastwdlaa nqlvk