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MULTISPECIES: HTH-type transcriptional regulator PtxR


LOCUS       WP_003089264             312 aa            linear   BCT 20-NOV-2023
            [Pseudomonas].
ACCESSION   WP_003089264
VERSION     WP_003089264.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 312)
  AUTHORS   Ferrell,E., Carty,N.L., Colmer-Hamood,J.A., Hamood,A.N. and
            West,S.E.H.
  TITLE     Regulation of Pseudomonas aeruginosa ptxR by Vfr
  JOURNAL   Microbiology (Reading) 154 (Pt 2), 431-439 (2008)
   PUBMED   18227247
REFERENCE   2  (residues 1 to 312)
  AUTHORS   Carty,N.L., Layland,N., Colmer-Hamood,J.A., Calfee,M.W., Pesci,E.C.
            and Hamood,A.N.
  TITLE     PtxR modulates the expression of QS-controlled virulence factors in
            the Pseudomonas aeruginosa strain PAO1
  JOURNAL   Mol Microbiol 61 (3), 782-794 (2006)
   PUBMED   16803594
REFERENCE   3  (residues 1 to 312)
  AUTHORS   Colmer-Hamood,J.A., Aramaki,H., Gaines,J.M. and Hamood,A.N.
  TITLE     Transcriptional analysis of the Pseudomonas aeruginosa toxA
            regulatory gene ptxR
  JOURNAL   Can J Microbiol 52 (4), 343-356 (2006)
   PUBMED   16699585
REFERENCE   4  (residues 1 to 312)
  AUTHORS   Chen,L., Yang,J., Yu,J., Yao,Z., Sun,L., Shen,Y. and Jin,Q.
  TITLE     VFDB: a reference database for bacterial virulence factors
  JOURNAL   Nucleic Acids Res 33 (Database issue), D325-D328 (2005)
   PUBMED   15608208
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR012786
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..312
                     /gene="ptxR"
     Protein         1..312
                     /product="HTH-type transcriptional regulator PtxR"
                     /calculated_mol_wt=34861
     Region          13..>56
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          101..297
                     /region_name="PBP2_CrgA_like"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulator CrgA and its related
                     homologs, contains the type 2 periplasmic binding domain;
                     cd08422"
                     /db_xref="CDD:176114"
     Site            order(111,115,154,168,170,232,249,276)
                     /site_type="active"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176114"
     Site            order(112..113,117..118,120..121,124,128,130..136,197,
                     226..230,237..238,241)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:176114"
ORIGIN      
        1 msaalerlnh lnlnhlyafv avaehnsfta aaealglsks llseqlrrle adlgiqlltr
       61 ttrrmtltdr gellfgvaqr mlgeldgals dvrdlqgeps grlritapqd fvkwhissvs
      121 aafirqfpkv qvemladdqf sdlvgqridl avrigwprds glhasklcdf qqvavatpgy
      181 laglppvlqp hdlarcewig htrlstpwtw tferqrerat vqtrgrllan ntlavyrlvl
      241 dgagvsvlps flvareiarg rlvrllpgwr lpqggiyaly psarympvrv rafieslreh
      301 lgrepfrlaq se