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MULTISPECIES: MFS transporter [Pseudomonas].


LOCUS       WP_003087861             403 aa            linear   BCT 23-DEC-2024
ACCESSION   WP_003087861
VERSION     WP_003087861.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 403)
  AUTHORS   Goddard,A.D., Bali,S., Mavridou,D.A., Luque-Almagro,V.M.,
            Gates,A.J., Dolores Roldan,M., Newstead,S., Richardson,D.J. and
            Ferguson,S.J.
  TITLE     The Paracoccus denitrificans NarK-like nitrate and nitrite
            transporters-probing nitrate uptake and nitrate/nitrite exchange
            mechanisms
  JOURNAL   Mol Microbiol 103 (1), 117-133 (2017)
   PUBMED   27696579
REFERENCE   2  (residues 1 to 403)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   3  (residues 1 to 403)
  AUTHORS   Fukuda,M., Takeda,H., Kato,H.E., Doki,S., Ito,K., Maturana,A.D.,
            Ishitani,R. and Nureki,O.
  TITLE     Structural basis for dynamic mechanism of nitrate/nitrite antiport
            by NarK
  JOURNAL   Nat Commun 6, 7097 (2015)
   PUBMED   25959928
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 403)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   5  (residues 1 to 403)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
REFERENCE   6  (residues 1 to 403)
  AUTHORS   Jia,W., Tovell,N., Clegg,S., Trimmer,M. and Cole,J.
  TITLE     A single channel for nitrate uptake, nitrite export and nitrite
            uptake by Escherichia coli NarU and a role for NirC in nitrite
            export and uptake
  JOURNAL   Biochem J 417 (1), 297-304 (2009)
   PUBMED   18691156
REFERENCE   7  (residues 1 to 403)
  AUTHORS   Law,C.J., Maloney,P.C. and Wang,D.N.
  TITLE     Ins and outs of major facilitator superfamily antiporters
  JOURNAL   Annu Rev Microbiol 62, 289-305 (2008)
   PUBMED   18537473
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11454872
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..403
                     /product="MFS transporter"
                     /GO_function="GO:0015112 - nitrate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=42226
     Region          12..347
                     /region_name="2A0108"
                     /note="nitrite extrusion protein (nitrite facilitator);
                     TIGR00886"
                     /db_xref="CDD:273322"
ORIGIN      
        1 mnnsfwkagh aptlfaafly fdlsfmvwyv lgplgvqiag dlqlstqqra mmvatpilag
       61 avlrfllgll adrwspksag ilaqviviaa laaawllgvn syaqalllgl flgfagasfa
      121 valplasqwy ppqhqgkamg iagagnsgtv laalfapgla aafgwnnvfg fallplvltl
      181 lvfamvarna pqrpapkamg dylkalgdrd swwfmffysv tfggflglas tlpgyfhdqy
      241 glnpvtagyy taacvfagsl mrplggalad riggirsllm vytlaaicia avgfhlpsam
      301 aalglfvvam lslgagngav fqlvpqrfhk eigvmtglig maggiggfcl taglgaikqs
      361 tgdyqlglwl faslgvlawf glhgvkrrwr ttwgsaavta arv