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MULTISPECIES: mechanosensitive ion channel family protein


LOCUS       WP_003087830             274 aa            linear   BCT 01-MAR-2025
            [Pseudomonas].
ACCESSION   WP_003087830
VERSION     WP_003087830.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 274)
  AUTHORS   Lai,J.Y., Poon,Y.S., Kaiser,J.T. and Rees,D.C.
  TITLE     Open and shut: crystal structures of the dodecylmaltoside
            solubilized mechanosensitive channel of small conductance from
            Escherichia coli and Helicobacter pylori at 4.4 A and 4.1 A
            resolutions
  JOURNAL   Protein Sci 22 (4), 502-509 (2013)
   PUBMED   23339071
REFERENCE   2  (residues 1 to 274)
  AUTHORS   Zhang,X., Wang,J., Feng,Y., Ge,J., Li,W., Sun,W., Iscla,I., Yu,J.,
            Blount,P., Li,Y. and Yang,M.
  TITLE     Structure and molecular mechanism of an anion-selective
            mechanosensitive channel of small conductance
  JOURNAL   Proc Natl Acad Sci U S A 109 (44), 18180-18185 (2012)
   PUBMED   23074248
REFERENCE   3  (residues 1 to 274)
  AUTHORS   Pliotas,C., Ward,R., Branigan,E., Rasmussen,A., Hagelueken,G.,
            Huang,H., Black,S.S., Booth,I.R., Schiemann,O. and Naismith,J.H.
  TITLE     Conformational state of the MscS mechanosensitive channel in
            solution revealed by pulsed electron-electron double resonance
            (PELDOR) spectroscopy
  JOURNAL   Proc Natl Acad Sci U S A 109 (40), E2675-E2682 (2012)
   PUBMED   23012406
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF017373.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF05552.17
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..274
                     /product="mechanosensitive ion channel family protein"
                     /calculated_mol_wt=28888
     Region          9..>145
                     /region_name="msc"
                     /note="mechanosensitive ion channel; NF033912"
                     /db_xref="CDD:468242"
     Region          102..>272
                     /region_name="MscK"
                     /note="Small-conductance mechanosensitive channel MscK
                     [Cell wall/membrane/envelope biogenesis]; COG3264"
                     /db_xref="CDD:442495"
ORIGIN      
        1 mqfdiwtqsl ltamntlwgk lagfipnllg alvvvllgfv iaklldalls kllaklgldr
       61 lmggtgltkl larvgiqvpv stlvgkivyw fvllvflvsa aeslglqrvs atldvlalyl
      121 pkvfgaalvl ivgvllaqlv nsvvrgaadg vgleyanglg riaqwlviii sisvavgqle
      181 vktdllnyii aivlitvgla aalalglgsr evagqiiagi yvrelyqvgq qvkvgdvegt
      241 ieeigtvkti llteegelvs lanrllldqr vtsr