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MULTISPECIES: macro domain-containing protein [Pseudomonas].


LOCUS       WP_003087757             168 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003087757
VERSION     WP_003087757.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 168)
  AUTHORS   Rack,J.G., Perina,D. and Ahel,I.
  TITLE     Macrodomains: Structure, Function, Evolution, and Catalytic
            Activities
  JOURNAL   Annu Rev Biochem 85, 431-454 (2016)
   PUBMED   26844395
REFERENCE   2  (residues 1 to 168)
  AUTHORS   Li,X., Wu,Z. and Han,W.
  TITLE     The macrodomain family: Rethinking an ancient domain from
            evolutionary perspectives
  JOURNAL   Chin Sci Bull 58 (9), 953-960 (2013)
   PUBMED   32214744
REFERENCE   3  (residues 1 to 168)
  AUTHORS   Han,W., Li,X. and Fu,X.
  TITLE     The macro domain protein family: structure, functions, and their
            potential therapeutic implications
  JOURNAL   Mutat Res 727 (3), 86-103 (2011)
   PUBMED   21421074
REFERENCE   4  (residues 1 to 168)
  AUTHORS   Karras,G.I., Kustatscher,G., Buhecha,H.R., Allen,M.D., Pugieux,C.,
            Sait,F., Bycroft,M. and Ladurner,A.G.
  TITLE     The macro domain is an ADP-ribose binding module
  JOURNAL   EMBO J 24 (11), 1911-1920 (2005)
   PUBMED   15902274
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10121048
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..168
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..168
                     /product="macro domain-containing protein"
                     /GO_function="GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /GO_function="GO:0072570 - ADP-D-ribose binding [Evidence
                     IEA]"
                     /calculated_mol_wt=18058
     Region          1..147
                     /region_name="Macro_Poa1p-like"
                     /note="macrodomain, Poa1p-like family; cd02901"
                     /db_xref="CDD:394873"
     Site            order(7..10,19..22,26..32,34,80..81,122..129)
                     /site_type="other"
                     /note="ADP-ribose binding site [chemical binding]"
                     /db_xref="CDD:394873"
ORIGIN      
        1 mirevegdil lsgaqviahg iapqdhfdsg lalalrerwp smvrdyrhaa harapepggi
       61 wvwagvdeqg ktqcivnlit qgmlhsgrsa kpgkasledv ghalrelary vrsegvssla
      121 lpcvatgvgg ldwsevkplv vrhlgdleip vilyevyrkg vaaeekla