MULTISPECIES: hydroxyisourate hydrolase [Pseudomonas].

LOCUS       WP_003087207             126 aa            linear   BCT 03-JUN-2024
ACCESSION   WP_003087207
VERSION     WP_003087207.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 126)
  AUTHORS   French,J.B. and Ealick,S.E.
  TITLE     Structural and kinetic insights into the mechanism of
            5-hydroxyisourate hydrolase from Klebsiella pneumoniae
  JOURNAL   Acta Crystallogr D Biol Crystallogr 67 (Pt 8), 671-677 (2011)
   PUBMED   21795808
REFERENCE   2  (residues 1 to 126)
  AUTHORS   Lee,Y., Park,B.C., Lee,D.H., Bae,K.H., Cho,S., Lee,C.H., Lee,J.S.,
            Myung,P.K. and Park,S.G.
  TITLE     Mouse transthyretin-related protein is a hydrolase which degrades
            5-hydroxyisourate, the end product of the uricase reaction
  JOURNAL   Mol Cells 22 (2), 141-145 (2006)
   PUBMED   17085964
REFERENCE   3  (residues 1 to 126)
  AUTHORS   Lee,Y., Lee,D.H., Kho,C.W., Lee,A.Y., Jang,M., Cho,S., Lee,C.H.,
            Lee,J.S., Myung,P.K., Park,B.C. and Park,S.G.
  TITLE     Transthyretin-related proteins function to facilitate the
            hydrolysis of 5-hydroxyisourate, the end product of the uricase
            reaction
  JOURNAL   FEBS Lett 579 (21), 4769-4774 (2005)
   PUBMED   16098976
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02962.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..126
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..126
                     /gene="uraH"
     Protein         1..126
                     /product="hydroxyisourate hydrolase"
                     /EC_number="3.5.2.17"
                     /GO_function="GO:0033971 - hydroxyisourate hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006144 - purine nucleobase metabolic
                     process [Evidence IEA]"
                     /calculated_mol_wt=13843
     Region          10..126
                     /region_name="HiuH"
                     /note="5-hydroxyisourate hydrolase (purine catabolism),
                     transthyretin-related family [Nucleotide transport and
                     metabolism]; COG2351"
                     /db_xref="CDD:441918"
ORIGIN      
        1 msasgrpqpm grltthvlds ahgcpghgik ielyrvegqq leliattltn hdgrcdqpvl
       61 qgedfrpgvy qlvfnagdyy rargvqlpep afldqvvlrf giasaddhyh vpllispysy
      121 styrgs