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MULTISPECIES: MFS transporter [Pseudomonas].


LOCUS       WP_003086798             399 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003086798
VERSION     WP_003086798.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 399)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 399)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 399)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024122
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..399
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=41760
     Region          5..384
                     /region_name="MFS_YcxA_like"
                     /note="MFS-type transporter YcxA and similar proteins of
                     the Major Facilitator Superfamily of transporters;
                     cd17355"
                     /db_xref="CDD:340913"
     Site            order(16..17,20..21,24,59,106..107,109..111,114,139,
                     142..143,146,214,217..218,221..223,226,256,260,310..311,
                     315,319,335,338..339,342..343,346)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340913"
ORIGIN      
        1 mpraafwill sgalilalsl gvrhgfglfl apmsadfgwg revfafaial qnlvwglaqp
       61 ftgaladryg aaravlvggl lyalglvlmg lsqsasglsl saglliglgl sgtsfsvilg
      121 avgravpaeq rsmamgissa agsfgqfaml pgtlgligwl gwssallalg llvalivpla
      181 glmkdrplpp qgheqslgea lreacahsgf wllalgffvc gfqvvfigvh lpaylvdqhl
      241 paqvgttvla lvglfnvfgt yiagwlggrw skprlltaly lvrgvvivlf lwlplsvysa
      301 yafgvamgll wlstvpltng tvatlfgvrn lsmlggivfl fhqlgaflgg wlggvvydrt
      361 gsydlvwqls illsllaall nwpvrerpva rlqvaggaa