MULTISPECIES: SDR family NAD(P)-dependent oxidoreductase

LOCUS       WP_003086302             305 aa            linear   BCT 02-MAR-2025
            [Pseudomonas].
ACCESSION   WP_003086302
VERSION     WP_003086302.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 305)
  AUTHORS   Yamashita,A., Kato,H., Wakatsuki,S., Tomizaki,T., Nakatsu,T.,
            Nakajima,K., Hashimoto,T., Yamada,Y. and Oda,J.
  TITLE     Structure of tropinone reductase-II complexed with NADP+ and
            pseudotropine at 1.9 A resolution: implication for stereospecific
            substrate binding and catalysis
  JOURNAL   Biochemistry 38 (24), 7630-7637 (1999)
   PUBMED   10387002
REFERENCE   2  (residues 1 to 305)
  AUTHORS   Benach,J., Atrian,S., Gonzalez-Duarte,R. and Ladenstein,R.
  TITLE     The refined crystal structure of Drosophila lebanonensis alcohol
            dehydrogenase at 1.9 A resolution
  JOURNAL   J Mol Biol 282 (2), 383-399 (1998)
   PUBMED   9735295
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF012334.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00106.31
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..305
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /calculated_mol_wt=32690
     Region          8..248
                     /region_name="Rossmann-fold NAD(P)(+)-binding proteins"
                     /note="A large family of proteins that share a
                     Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The
                     NADB domain is found in numerous dehydrogenases of
                     metabolic pathways such as glycolysis, and many other
                     redox enzymes. NAD binding involves numerous...; cl21454"
                     /db_xref="CDD:473865"
     Site            order(15,17..18,20,39..41,101..103,151..153,166,170,
                     196..199)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:187535"
     Site            order(125,153,166,170)
                     /site_type="active"
                     /db_xref="CDD:187535"
ORIGIN      
        1 mssrlnegkv aivtgagggi greialalad sgarvvindi gvslqgeggs aspaeetlgl
       61 irqrggegli ntdsvadwds arrivecamd gfgrldivvn nagilrdaif hkmsaddwls
      121 vinvhlngsf fvsraaaerf rtqqagafvh mtstsglign fgqanysaak lgivalsksi
      181 aldmqrynvr snciapfaws rmtdsipaet peqkarvdkl qrmtpeknap lavylasdaa
      241 revtgqvfaa rhhelflmsq srplrsvhse hgwtpesiae hgmpalrgsf mdlarspdvf
      301 swdpi