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MULTISPECIES: methylated-DNA--[protein]-cysteine


LOCUS       WP_003086236             173 aa            linear   BCT 31-DEC-2024
            S-methyltransferase [Pseudomonas].
ACCESSION   WP_003086236
VERSION     WP_003086236.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 173)
  AUTHORS   Margison,G.P., Butt,A., Pearson,S.J., Wharton,S., Watson,A.J.,
            Marriott,A., Caetano,C.M., Hollins,J.J., Rukazenkova,N., Begum,G.
            and Santibanez-Koref,M.F.
  TITLE     Alkyltransferase-like proteins
  JOURNAL   DNA Repair (Amst) 6 (8), 1222-1228 (2007)
   PUBMED   17500045
REFERENCE   2  (residues 1 to 173)
  AUTHORS   Tubbs,J.L., Pegg,A.E. and Tainer,J.A.
  TITLE     DNA binding, nucleotide flipping, and the helix-turn-helix motif in
            base repair by O6-alkylguanine-DNA alkyltransferase and its
            implications for cancer chemotherapy
  JOURNAL   DNA Repair (Amst) 6 (8), 1100-1115 (2007)
   PUBMED   17485252
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11417447
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..173
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..173
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /EC_number="2.1.1.63"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /calculated_mol_wt=19122
     Region          5..158
                     /region_name="AdaB"
                     /note="DNA repair enzyme Ada
                     (O6-methylguanine-DNA--protein-cysteine methyltransferase)
                     [Replication, recombination and repair]; COG0350"
                     /db_xref="CDD:440119"
ORIGIN      
        1 mphsyrkmes pvgtltlvar ddaflvailw qherpnrvpl demrlsedss llaeterqlr
       61 eyfsgkrsrf elpldfqgte fqkkvwsall tipfgetrsy teiavqigsp navravgaan
      121 grnplsivap chrvigasgg ltgfagglaa kqwllrletr grtpdllsmi ede