MULTISPECIES: 4a-hydroxytetrahydrobiopterin dehydratase [Bacteria].

LOCUS       WP_003085898             118 aa            linear   BCT 06-AUG-2024
ACCESSION   WP_003085898
VERSION     WP_003085898.1
KEYWORDS    RefSeq.
SOURCE      Bacteria (eubacteria)
  ORGANISM  Bacteria
            Unclassified.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002016.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00823
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..118
                     /organism="Bacteria"
                     /db_xref="taxon:2"
     Protein         1..118
                     /product="4a-hydroxytetrahydrobiopterin dehydratase"
                     /EC_number="4.2.1.96"
                     /GO_function="GO:0008124 -
                     4-alpha-hydroxytetrahydrobiopterin dehydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006729 - tetrahydrobiopterin biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=13202
     Region          14..112
                     /region_name="phhB"
                     /note="pterin-4-alpha-carbinolamine dehydratase;
                     Validated; PRK00823"
                     /db_xref="CDD:234845"
     Site            order(54,58,74,77,91)
                     /site_type="other"
                     /note="aromatic arch"
                     /db_xref="CDD:238455"
     Site            order(54..55,58,62,69,74,76..80)
                     /site_type="other"
                     /note="DCoH dimer interaction site [polypeptide binding]"
                     /db_xref="CDD:238455"
     Site            order(55..56,62..63,66,69..70)
                     /site_type="other"
                     /note="DCoH /HNF-1 dimer interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:238455"
     Site            order(55,62..63,66,70)
                     /site_type="other"
                     /note="DCoH tetramer interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:238455"
     Site            order(72..74,89,91..92)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:238455"
ORIGIN      
        1 mtaltqahce acradaphvs deelpvllrq ipdwnievrd gimqlekvyl fknfkhalaf
       61 tnavgeisea eghhpgllte wgkvtvtwws hsikglhrnd fimaartdev aktaegrk