MULTISPECIES: translation elongation factor 4 [Pseudomonas].

LOCUS       WP_003085555             599 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003085555
VERSION     WP_003085555.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 599)
  AUTHORS   Gibbs,M.R., Moon,K.M., Chen,M., Balakrishnan,R., Foster,L.J. and
            Fredrick,K.
  TITLE     Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis
            of the 30S subunit of the 70S ribosome
  JOURNAL   Proc Natl Acad Sci U S A 114 (5), 980-985 (2017)
   PUBMED   28096346
REFERENCE   2  (residues 1 to 599)
  AUTHORS   Song,G. and Qin,Y.
  TITLE     EF4 reveals the energy barrier for tRNA back-translocation in the
            peptidyl transferase center
  JOURNAL   RNA Biol 13 (10), 934-939 (2016)
   PUBMED   27472653
REFERENCE   3  (residues 1 to 599)
  AUTHORS   Kumar,V., Ero,R., Ahmed,T., Goh,K.J., Zhan,Y., Bhushan,S. and
            Gao,Y.G.
  TITLE     Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the
            Ribosome
  JOURNAL   J Biol Chem 291 (25), 12943-12950 (2016)
   PUBMED   27137929
REFERENCE   4  (residues 1 to 599)
  AUTHORS   Liu,H., Chen,C., Zhang,H., Kaur,J., Goldman,Y.E. and Cooperman,B.S.
  TITLE     The conserved protein EF4 (LepA) modulates the elongation cycle of
            protein synthesis
  JOURNAL   Proc Natl Acad Sci U S A 108 (39), 16223-16228 (2011)
   PUBMED   21930951
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01393.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..599
                     /gene="lepA"
     Protein         1..599
                     /product="translation elongation factor 4"
                     /EC_number="3.6.5.n1"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /calculated_mol_wt=66164
     Region          2..598
                     /region_name="LepA"
                     /note="Translation elongation factor EF-4, membrane-bound
                     GTPase [Translation, ribosomal structure and biogenesis];
                     COG0481"
                     /db_xref="CDD:440249"
ORIGIN      
        1 msdlshirnf siiahidhgk stladrfiqm cgglsdreme aqvldsmdle rergitikah
       61 svtlhykaqd gktyqlnfid tpghvdftye vsrslaaceg allvvdagqg veaqsvancy
      121 taieqglevm pvlnkmdlpq aepervkeei esiigidatd avacsaksgm gvlevlerlv
      181 taipapegei eaplqaliid swfdnylgvv slvrvkngrv kkgdkilvks tgkvhqvdsv
      241 gvftpkhtet vdlkagevgf iiagikdihg apvgdtltln ntpdvevlpg fkrvkpqvya
      301 glfpvssddf edfrdalqkl tlndsslqye pessealgfg frcgflgmlh meiiqerler
      361 eydldlitta ptvvfeivqk ngeiiyvdnp sklpdlasiq emrepicrat ilvpkdhlgn
      421 vitlciekrg vqrdmhflsg qvqvvydlpm nevvldffdr lkstsrgyas ldysfdrfep
      481 snlvrldvli ngekvdalal ivhrdnapyk grqlvekmke liprqmfdva iqaaiggqii
      541 arstvkalrk nvlakcyggd vsrkrkllek qkagkkrmkq vgsveipqea flavlkvds