MULTISPECIES: biliverdin-producing heme oxygenase PigA

LOCUS       WP_003085321             198 aa            linear   BCT 27-MAR-2021
            [Gammaproteobacteria].
ACCESSION   WP_003085321
VERSION     WP_003085321.1
KEYWORDS    RefSeq.
SOURCE      Gammaproteobacteria
  ORGANISM  Gammaproteobacteria
            Bacteria; Pseudomonadati; Pseudomonadota.
REFERENCE   1  (residues 1 to 198)
  AUTHORS   Friedman,J., Lad,L., Li,H., Wilks,A. and Poulos,T.L.
  TITLE     Structural basis for novel delta-regioselective heme oxygenation in
            the opportunistic pathogen Pseudomonas aeruginosa
  JOURNAL   Biochemistry 43 (18), 5239-5245 (2004)
   PUBMED   15122889
REFERENCE   2  (residues 1 to 198)
  AUTHORS   Caignan,G.A., Deshmukh,R., Wilks,A., Zeng,Y., Huang,H.W.,
            Moenne-Loccoz,P., Bunce,R.A., Eastman,M.A. and Rivera,M.
  TITLE     Oxidation of heme to beta- and delta-biliverdin by Pseudomonas
            aeruginosa heme oxygenase as a consequence of an unusual seating of
            the heme
  JOURNAL   J Am Chem Soc 124 (50), 14879-14892 (2002)
   PUBMED   12475329
REFERENCE   3  (residues 1 to 198)
  AUTHORS   Ratliff,M., Zhu,W., Deshmukh,R., Wilks,A. and Stojiljkovic,I.
  TITLE     Homologues of neisserial heme oxygenase in gram-negative bacteria:
            degradation of heme by the product of the pigA gene of Pseudomonas
            aeruginosa
  JOURNAL   J Bacteriol 183 (21), 6394-6403 (2001)
   PUBMED   11591684
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR013462
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..198
                     /organism="Gammaproteobacteria"
                     /db_xref="taxon:1236"
     gene            1..198
                     /gene="pigA"
     Protein         1..198
                     /product="biliverdin-producing heme oxygenase PigA"
                     /EC_number="1.14.99.58"
                     /calculated_mol_wt=21822
     Region          14..195
                     /region_name="HemeO-like"
                     /note="heme oxygenase; cd00232"
                     /db_xref="CDD:350855"
     Site            order(19,26,29..30,55,117..119,121..122,128,158,162,186,
                     189,193)
                     /site_type="other"
                     /note="heme binding site [chemical binding]"
                     /db_xref="CDD:350855"
     Region          110..135
                     /region_name="kinked helix"
                     /note="kinked helix [structural motif]"
                     /db_xref="CDD:350855"
ORIGIN      
        1 mdtlapestr qnlrsqrlnl ltnephqrle slvkskepfa srdnfarfva aqylfqhdle
       61 plyrnealar lfpglasrar ddaaradlad lghpvpegdq svreadlsla ealgwlfvse
      121 gsklgaaflf kkaaalelde nfgarhlaep eggraqgwks fvaildgiel neeeerlaak
      181 gasdafnrfg dllertfa