MULTISPECIES: spermidine-binding protein SpuE [Bacteria].

LOCUS       WP_003084301             365 aa            linear   BCT 24-JUL-2024
ACCESSION   WP_003084301
VERSION     WP_003084301.1
KEYWORDS    RefSeq.
SOURCE      Bacteria (eubacteria)
  ORGANISM  Bacteria
            Unclassified.
REFERENCE   1  (residues 1 to 365)
  AUTHORS   Zhang,Y., Sun,X., Qian,Y., Yi,H., Song,K., Zhu,H., Zonta,F.,
            Chen,W., Ji,Q., Miersch,S., Sidhu,S.S. and Wu,D.
  TITLE     A Potent Anti-SpuE Antibody Allosterically Inhibits Type III
            Secretion System and Attenuates Virulence of Pseudomonas Aeruginosa
  JOURNAL   J Mol Biol 431 (24), 4882-4896 (2019)
   PUBMED   31682834
REFERENCE   2  (residues 1 to 365)
  AUTHORS   Wu,D., Lim,S.C., Dong,Y., Wu,J., Tao,F., Zhou,L., Zhang,L.H. and
            Song,H.
  TITLE     Structural basis of substrate binding specificity revealed by the
            crystal structures of polyamine receptors SpuD and SpuE from
            Pseudomonas aeruginosa
  JOURNAL   J Mol Biol 416 (5), 697-712 (2012)
   PUBMED   22300763
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR014647
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Bacteria"
                     /db_xref="taxon:2"
     gene            1..365
                     /gene="spuE"
     Protein         1..365
                     /product="spermidine-binding protein SpuE"
                     /calculated_mol_wt=39939
     Region          29..358
                     /region_name="PBP2_PotF"
                     /note="The periplasmic substrate-binding component of an
                     ABC putrescine transport system and related proteins;
                     contains the type 2 periplasmic-binding fold; cd13659"
                     /db_xref="CDD:270377"
     Site            order(34,239,242,271,273,309)
                     /site_type="other"
                     /note="chemical substrate binding site [chemical binding]"
                     /db_xref="CDD:270377"
     Site            order(45,48..49,297..298)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:270377"
ORIGIN      
        1 mqhsigktll vaalataiag pvqaekkslh iynwtdyiap ttlkdftkes gidvsydvfd
       61 snetlegklv sghsgydivv psnnflgkqi qagafqkldk sklpnwknld pallkqlevs
      121 dpgnqyavpy lwgtngigyn vakvkevlgd qpidswailf epenmkklak cgvafmdsgd
      181 emlpaalnyl gldpnthdpk dykkaeevlt kvrpyvsyfh sskyisdlan gnicvafgys
      241 gdvfqaaara eeagkgidiq yvipkeganl wfdlmaipad akaadnayaf idyllrpevi
      301 akvsdyvgya naipgarplm dksvsdseev yppqavldkl yvsavlpakv lrlqtrtwtr
      361 iktgk