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MULTISPECIES: protein-glutamate methylesterase/protein-glutamine


LOCUS       WP_003083922             349 aa            linear   BCT 20-JAN-2025
            glutaminase [Pseudomonas].
ACCESSION   WP_003083922
VERSION     WP_003083922.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 349)
  AUTHORS   Galperin,M.Y.
  TITLE     Structural classification of bacterial response regulators:
            diversity of output domains and domain combinations
  JOURNAL   J Bacteriol 188 (12), 4169-4182 (2006)
   PUBMED   16740923
REFERENCE   2  (residues 1 to 349)
  AUTHORS   Skerker,J.M., Prasol,M.S., Perchuk,B.S., Biondi,E.G. and Laub,M.T.
  TITLE     Two-component signal transduction pathways regulating growth and
            cell cycle progression in a bacterium: a system-level analysis
  JOURNAL   PLoS Biol 3 (10), e334 (2005)
   PUBMED   16176121
REFERENCE   3  (residues 1 to 349)
  AUTHORS   Stock,A.M., Robinson,V.L. and Goudreau,P.N.
  TITLE     Two-component signal transduction
  JOURNAL   Annu Rev Biochem 69, 183-215 (2000)
   PUBMED   10966457
REFERENCE   4  (residues 1 to 349)
  AUTHORS   Djordjevic,S. and Stock,A.M.
  TITLE     Structural analysis of bacterial chemotaxis proteins: components of
            a dynamic signaling system
  JOURNAL   J Struct Biol 124 (2-3), 189-200 (1998)
   PUBMED   10049806
REFERENCE   5  (residues 1 to 349)
  AUTHORS   Anand,G.S., Goudreau,P.N. and Stock,A.M.
  TITLE     Activation of methylesterase CheB: evidence of a dual role for the
            regulatory domain
  JOURNAL   Biochemistry 37 (40), 14038-14047 (1998)
   PUBMED   9760239
REFERENCE   6  (residues 1 to 349)
  AUTHORS   Volz,K.
  TITLE     Structural conservation in the CheY superfamily
  JOURNAL   Biochemistry 32 (44), 11741-11753 (1993)
   PUBMED   8218244
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11479194
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..349
                     /product="protein-glutamate
                     methylesterase/protein-glutamine glutaminase"
                     /EC_number="3.1.1.61"
                     /EC_number="3.5.1.44"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0008984 - protein-glutamate
                     methylesterase activity [Evidence IEA]"
                     /GO_function="GO:0050568 - protein-glutamine glutaminase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006482 - protein demethylation [Evidence
                     IEA]"
                     /GO_process="GO:0006935 - chemotaxis [Evidence IEA]"
                     /GO_process="GO:0018277 - protein deamination [Evidence
                     IEA]"
                     /calculated_mol_wt=37216
     Region          1..332
                     /region_name="PRK00742"
                     /note="chemotaxis-specific protein-glutamate
                     methyltransferase CheB"
                     /db_xref="CDD:234828"
ORIGIN      
        1 mpisvlvvdd salirsllke iiqadpelrl vgcapdafva rdlikqhapd visldvempr
       61 mdgltfldkl mkarptpvlm issltergse atlralelga vdfiakprlg iaegmqayae
      121 eiraklktva rarlrrraad apappesaap llstekiial gastggteal kevllglpah
      181 spgvvitqhm ppgftrsfae rldrltrlsv seardgdril pghalvapgd hhmevqrsga
      241 nyvvrlnrqa qvnghrpavd vmfeslarca grnllagllt gmgkdgargl lairqaggyt
      301 laqdeatcvv ygmpreavel gaaedvlple riaaallqqa arrgsgnrl