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MULTISPECIES: helix-turn-helix transcriptional regulator


LOCUS       WP_003083105             323 aa            linear   BCT 24-DEC-2024
            [Pseudomonas].
ACCESSION   WP_003083105
VERSION     WP_003083105.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 323)
  AUTHORS   Keller,L.M. and Weber-Ban,E.
  TITLE     An emerging class of nucleic acid-sensing regulators in bacteria:
            WYL domain-containing proteins
  JOURNAL   Curr Opin Microbiol 74, 102296 (2023)
   PUBMED   37027901
REFERENCE   2  (residues 1 to 323)
  AUTHORS   Makarova,K.S., Anantharaman,V., Grishin,N.V., Koonin,E.V. and
            Aravind,L.
  TITLE     CARF and WYL domains: ligand-binding regulators of prokaryotic
            defense systems
  JOURNAL   Front Genet 5, 102 (2014)
   PUBMED   24817877
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 323)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   4  (residues 1 to 323)
  AUTHORS   Rosinski,J.A. and Atchley,W.R.
  TITLE     Molecular evolution of helix-turn-helix proteins
  JOURNAL   J Mol Evol 49 (3), 301-309 (1999)
   PUBMED   10473770
REFERENCE   5  (residues 1 to 323)
  AUTHORS   Wintjens,R. and Rooman,M.
  TITLE     Structural classification of HTH DNA-binding domains and
            protein-DNA interaction modes
  JOURNAL   J Mol Biol 262 (2), 294-313 (1996)
   PUBMED   8831795
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11457199
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..323
                     /product="helix-turn-helix transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=36128
     Region          3..315
                     /region_name="YobV"
                     /note="Predicted DNA-binding transcriptional regulator
                     YobV, contains HTH and WYL domains [Transcription];
                     COG2378"
                     /db_xref="CDD:441945"
ORIGIN      
        1 mskptvrvla llellqshgq lsgselarrl evdgrtlrry ivaleelgip isaergrhgg
       61 yrlvagfklp plmfsaeetl avslgllavr slglgesela lesaqaklsr vmpvalrrrl
      121 valretasld lararagtsv aalatlaeaa qvrarvefry rdpqgaetlr qldpyglayr
      181 ngcwyvsgfc hlrqalrsfr ldrldaprml aerferpadf dtlrhlresf armpraypve
      241 ilmraareqv vavlgeplgl laevdggtll rastddldwf arrlcglpfd fevrqplelr
      301 eplrrqaerv lrnlgqeeas dhr