Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: transcriptional regulator LasR [Gammaproteobacteria].


LOCUS       WP_003082999             239 aa            linear   BCT 02-SEP-2023
ACCESSION   WP_003082999
VERSION     WP_003082999.1
KEYWORDS    RefSeq.
SOURCE      Gammaproteobacteria
  ORGANISM  Gammaproteobacteria
            Bacteria; Pseudomonadati; Pseudomonadota.
REFERENCE   1  (residues 1 to 239)
  AUTHORS   Kim,E.J., Wang,W., Deckwer,W.D. and Zeng,A.P.
  TITLE     Expression of the quorum-sensing regulatory protein LasR is
            strongly affected by iron and oxygen concentrations in cultures of
            Pseudomonas aeruginosa irrespective of cell density
  JOURNAL   Microbiology (Reading) 151 (Pt 4), 1127-1138 (2005)
   PUBMED   15817780
REFERENCE   2  (residues 1 to 239)
  AUTHORS   Fukushima,J., Ishiwata,T., Kurata,M., You,Z. and Okuda,K.
  TITLE     Intracellular receptor-type transcription factor, LasR, contains a
            highly conserved amphipathic region which precedes the putative
            helix-turn-helix DNA binding motif
  JOURNAL   Nucleic Acids Res 22 (18), 3706-3707 (1994)
   PUBMED   7937080
REFERENCE   3  (residues 1 to 239)
  AUTHORS   Gambello,M.J. and Iglewski,B.H.
  TITLE     Cloning and characterization of the Pseudomonas aeruginosa lasR
            gene, a transcriptional activator of elastase expression
  JOURNAL   J Bacteriol 173 (9), 3000-3009 (1991)
   PUBMED   1902216
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR013453
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..239
                     /organism="Gammaproteobacteria"
                     /db_xref="taxon:1236"
     gene            1..239
                     /gene="lasR"
     Protein         1..239
                     /product="transcriptional regulator LasR"
                     /calculated_mol_wt=26487
     Region          18..161
                     /region_name="Autoind_bind"
                     /note="Autoinducer binding domain; pfam03472"
                     /db_xref="CDD:427319"
     Region          175..231
                     /region_name="GerE"
                     /note="Bacterial regulatory proteins, luxR family;
                     pfam00196"
                     /db_xref="CDD:425517"
     Site            order(178..180,193..195,203..204,206..207,209..213,224)
                     /site_type="DNA binding"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     Site            order(189,191,193,224..226,229,232..233)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:99777"
ORIGIN      
        1 malvdgflel erssgklews ailqkmasdl gfskilfgll pkdsqdyena fivgnypaaw
       61 rehydragya rvdptvshct qsvlpifwep siyqtrkqhe ffeeasaagl vygltmplhg
      121 argelgalsl sveaenraea nrfmesvlpt lwmlkdyalq sgaglafehp vskpvvltsr
      181 ekevlqwcai gktsweisvi cncseanvnf hmgnirrkfg vtsrrvaaim avnlglitl