MULTISPECIES: NAD(P)H-dependent oxidoreductase [Pseudomonas].

LOCUS       WP_003082512             208 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003082512
VERSION     WP_003082512.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 208)
  AUTHORS   Ullmann,E., Tan,T.C., Gundinger,T., Herwig,C., Divne,C. and
            Spadiut,O.
  TITLE     A novel cytosolic NADH:quinone oxidoreductase from
            Methanothermobacter marburgensis
  JOURNAL   Biosci Rep 34 (6), e00167 (2014)
   PUBMED   25372605
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 208)
  AUTHORS   Li,R., Bianchet,M.A., Talalay,P. and Amzel,L.M.
  TITLE     The three-dimensional structure of NAD(P)H:quinone reductase, a
            flavoprotein involved in cancer chemoprotection and chemotherapy:
            mechanism of the two-electron reduction
  JOURNAL   Proc Natl Acad Sci U S A 92 (19), 8846-8850 (1995)
   PUBMED   7568029
  REMARK    Erratum:[Proc Natl Acad Sci U S A 1995 Nov 7;92(23):10815]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10006206
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..208
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..208
                     /product="NAD(P)H-dependent oxidoreductase"
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /calculated_mol_wt=22420
     Region          2..192
                     /region_name="MdaB"
                     /note="Putative NADPH-quinone reductase (modulator of drug
                     activity B) [General function prediction only]; COG2249"
                     /db_xref="CDD:441850"
ORIGIN      
        1 mhalivvahh hprslthala ariaegvvra ghsaetadla aegfeprfgl adhavhrgqa
       61 sppadvlaeq aridradtlv lvypiywwsm pallkgwidr vfsngwafdy siggdlrkkl
      121 qrlrvvlvgv ggadagtfer hgyagamrtq idhgifdycg arvvrselll esesadpirh
      181 ldqalhigsq lfaargaqga aqaqplea