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MULTISPECIES: LysR family transcriptional regulator [Klebsiella].


LOCUS       WP_002923147             408 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_002923147
VERSION     WP_002923147.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 408)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 408)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444297
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..408
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /calculated_mol_wt=44792
     Region          14..71
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          112..170
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          200..397
                     /region_name="Periplasmic_Binding_Protein_Type_2"
                     /note="Type 2 periplasmic binding fold superfamily;
                     cl21456"
                     /db_xref="CDD:473866"
     Site            order(215..216,218..219,222,226,228..234,328..333,
                     339..340,342..343)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:176102"
ORIGIN      
        1 mlkrkhdkii nimqlrffcq valrgsvsra addlfrtqsa itrairdlea alnvtlferh
       61 ysgmvpteyg kcilprarra iddlqaipal lqkhhtrssg pladagwlfn trrlaifiql
      121 yhvnhtqtva qqlgitqpav saalkvlekg adsalfrrtp egvrptpaae llyppvsral
      181 neleniwsdl aarrgvlegt vrigalplsr trllpsaiaa flaqhpgitl mtnespyesl
      241 vadmragnid fiigalrqde dlpdlcseal feedmlillr nnhpllrhpd prsqlataqw
      301 vlpranapar nlldkafvtl glplpqptve tgdaamvrgl lqgsdmlaav sasqmrfetd
      361 ngllsvlpvp lpdttrrigl tfragslpsp atqallrfiy qqvqdgav