MULTISPECIES: NAD(P)-dependent alcohol dehydrogenase [Klebsiella].

LOCUS       WP_002922967             349 aa            linear   BCT 31-MAR-2023
ACCESSION   WP_002922967
VERSION     WP_002922967.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10143012
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..349
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /calculated_mol_wt=37270
     Region          10..343
                     /region_name="CAD1"
                     /note="Cinnamyl alcohol dehydrogenases (CAD); cd05283"
                     /db_xref="CDD:176186"
     Site            order(40..42,45,158,162,182..187,205..206,210,225,
                     244..245,247,267..268,292..294)
                     /site_type="other"
                     /note="putative NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:176186"
     Site            order(40,42,62,88,158,294)
                     /site_type="other"
                     /note="putative substrate binding site [chemical binding]"
                     /db_xref="CDD:176186"
     Site            order(40,62,158)
                     /site_type="other"
                     /note="catalytic Zn binding site [ion binding]"
                     /db_xref="CDD:176186"
     Site            order(93,96,99,107)
                     /site_type="other"
                     /note="structural Zn binding site [ion binding]"
                     /db_xref="CDD:176186"
     Site            order(106,165,169,261,266..268,270,280,282..283,286..293)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:176186"
ORIGIN      
        1 mlinaigtys asqplesmai trrdpgpqdv qiaiaycgvc hsdlhqarse wagtlypcvp
       61 gheivgrvta vgnavsryav gdlvgvgcmv dscqqceeca eglenycdhm vltyngptqd
      121 apghtlggys qqivvneryv lrithpeaql aavapllcag ittysplrhw hvgpgkkvgv
      181 vgigglghmg iklahamgah vvafttsesk rnaaralgad dvvvsrnede maahvksfdf
      241 ilntvaaphn ldafttllkr dgtmtlvgap atphpspevf nlifrrrsia gsmiggipet
      301 qemldfcaeh givadielir gdeineawer mvkgdvkyrf vidsatlag