MULTISPECIES: nucleobase:cation symporter-2 family protein

LOCUS       WP_002922950             463 aa            linear   BCT 23-DEC-2024
            [Klebsiella].
ACCESSION   WP_002922950
VERSION     WP_002922950.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 463)
  AUTHORS   Chaliotis,A., Vlastaridis,P., Ntountoumi,C., Botou,M., Yalelis,V.,
            Lazou,P., Tatsaki,E., Mossialos,D., Frillingos,S. and
            Amoutzias,G.D.
  TITLE     NAT/NCS2-hound: a webserver for the detection and evolutionary
            classification of prokaryotic and eukaryotic nucleobase-cation
            symporters of the NAT/NCS2 family
  JOURNAL   Gigascience 7 (12), 5168872 (2018)
   PUBMED   30418564
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 463)
  AUTHORS   Frillingos,S.
  TITLE     Insights to the evolution of Nucleobase-Ascorbate Transporters
            (NAT/NCS2 family) from the Cys-scanning analysis of xanthine
            permease XanQ
  JOURNAL   Int J Biochem Mol Biol 3 (3), 250-272 (2012)
   PUBMED   23097742
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10795438
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..463
                     /product="nucleobase:cation symporter-2 family protein"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /calculated_mol_wt=48500
     Region          29..457
                     /region_name="ncs2"
                     /note="uracil-xanthine permease; TIGR00801"
                     /db_xref="CDD:273276"
ORIGIN      
        1 msvntaesen aqpvahkpas eliyrledrp plpqtlfaaf qhllamfvav itpallicqa
       61 lglpaqdtqh iismslfasg vasiiqikaw gpvgsgllsi qgtsfnfvap limggtalkt
      121 ggadvptmma alfgtlmlas ctemvlsril hlarriitpl vsgvvvmiig lsliqvglts
      181 igggyaamad htfgapknll lagivlalii ilnrqrnpyl riaslviama agylaawfld
      241 mlpantaptn sslitvptpl yyglgidwsl llplmlvfmi tsletigdit atsdvseqpv
      301 sgplymkrlk ggvlanglns fvsavfntfp nscfgqnngv iqltgvasry vgfvvalmli
      361 vlglfpavsg fvqhipepvl ggatlvmfgt iaasgvrivs replnrrail iialslavgl
      421 gvsqqplilq fapdwlknll ssgiaaggit aivlnlifpp eka